PURPOSE Artificial tear formulations typically contain a water-soluble polymer to enhance residence time, moisture retention, and binding to the mucin coat of the ocular surface, which facilitate corneal healing. This study investigated the potential advantages of combining carboxymethylcellulose (CMC) and hyaluronic acid (HA) polymers in a single formulation. MATERIALS AND METHODS Individual...

Protein-surfactant mixtures arise in many industrial and biological systems, and indeed, blood itself is a mixture of serum albumins along with various other surface-active components. Bovine serum albumin (BSA) solutions, and globular proteins in general, exhibit an apparent yield stress in bulk rheological measurements at surprisingly low concentrations. By contrasting interfacial rheological...

A viscous Newtonian fluid and two model polystyrene Boger fluids are used to investigate the evolution of free-surface instabilities during the debonding of two cylindrical parallel rigid surfaces. A filament stretching rheometer is used to separate the surfaces at an exponential rate and simultaneously measure the evolution in the axial force. The experimental configuration also allows for sim...