نتایج جستجو برای: rhd k562 cell line
تعداد نتایج: 1971298 فیلتر نتایج به سال:
OBJECTIVE To estimate the accuracy of a new assay to determine the fetal RHD status using circulating cell-free DNA. METHODS This was a prospective, observational study. Maternal blood samples were collected in each trimester of pregnancy in 520 nonalloimmunized RhD-negative patients. Plasma samples were analyzed for circulating cell-free DNA using the SensiGENE RHD test, which used primers f...
Leukemia is the most common malignant disease in children with high incidence and mortality rates, and a poor treatment effect. The aim of the present study was to examine the changes in the expression of homeobox (Hox) A5 gene and its relationship with cell cycle and apoptosis through the intervention of human K562 myeloid leukemia cell line by all-trans retinoic acid (ATRA), to analyze the ro...
Title: Isorhamnetin 3-O-robinobioside from Nitraria retusa leaves enhance antioxidant and antigenotoxic activity in human chronic myelogenous leukemia cell line K562
which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Natural killer (NK) cells are derived from CD34＋ hematopoietic progenitor cells. NK cells are lymphocytes of the innate immune system that function as both cytotoxic effectors and immunoregulatory cells secreting cytokines and chemokines. However, considerab...
shiga toxins (stxs) are bacterial virulence factors produced by shigella dysenteriae serotype 1 and escherichia coli strains. stxs are critical factors for the development of diseases such as severe bloody diarrhea and hemolytic uremic syndrome. additionally, stxs trigger the secretion of pro- inflammatory cytokines and chemokines, particularly in monocytes or macrophages. the inflammatory cyto...
زمینه و هدف: ساخت و ترکیب داروهای جدید گیاهی و شیمیایی علیه بیماری هایی مثل سرطان، از جمله تلاش های مهم سال های اخیر محسوب می شود. ترکیبات ترپنی از جمله ترکیبات مهمی هستند که خواص بیولوژیکی و فارماکولوژیکی متعددی دارند، اما به دلیل حلالیت کم آن ها در محلول های آبی کمتر مورد توجه بوده اند. سیکلودکسترین ها نیز نانوکپسول های طبیعی تشکیل شده از واحدهای گلوکزی هستند که می توانند ایجاد نانوحفره نماین...
The static random-access memory (SRAM) cells used in the high radiation environment of aerospace have become highly vulnerable to single-event effects (SEE). Therefore, a 12T SRAM-hardened circuit (RHB-12T cell) for soft error recovery is proposed using hardening design (RHBD) concept. To verify performance RHB-12T, cell simulated by 28 nm CMOS process and compared with other hardened (Quatro-1...
PURPOSE Despite significant improvements in treatment of chronic myelogenous leukemia (CML), the emergence of leukemic stem cell (LSC) concept questioned efficacy of current therapeutical protocols. Remaining issue on CML includes finding and targeting of the key genes responsible for self-renewal and proliferation of LSCs. Nucleostemin (NS) is a new protein localized in the nucleolus of most s...
PURPOSE Although dual src-family kinase/BCR/ABL inhibitor, dasatinib (BMS-354825), provides therapeutic advantages to imatinib-resistant cells, the mechanism of dasatinib resistance was not fully known. EXPERIMENTAL DESIGN We used TF-1 BCR/ABL cells, by introducing the BCR/ABL gene into a leukemia cell line, TF-1 and K562, and established dasatinib- (BMS-R) and imatinib-resistant (IM-R) cells...
polar, hydrophilic compounds is an important prerequisite for the detoxification and eventual elimination of xenobiotics from the body. This mechanism also provides the first line of intracellular defense and is mediated by a number of enzyme superfamilies, including cytochrome P450 (CYP) and several conjugation enzymes including the sulfotransferases, UDPglucuronosyl transferases and glutathio...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید