نتایج جستجو برای: retina
تعداد نتایج: 51764 فیلتر نتایج به سال:
PURPOSE To develop large-scale, high-throughput annotation of the human macula transcriptome and to identify and prioritize candidate genes for inherited retinal dystrophies, based on ocular-expression profiles using serial analysis of gene expression (SAGE). METHODS Two human retina and two retinal pigment epithelium (RPE)/choroid SAGE libraries made from matched macula or midperipheral reti...
Timing between action potentials is crucial for information processing in real neural networks. However, the physical axonal lengths largely determine time necessary to reach postsynaptic neurons. Retinal ganglion cell (RGC) axons form retinal nerve fiber layer (RNFL). The human RNFL shows a highly stereotypical organization characterized by presence of fovea, specialized region enabling high-r...
PURPOSE Human vitreoretinal diseases are due to presumed abnormal mechanical interactions between the vitreous and retina, and translational models are limited. This study determined whether nonstructural proteins and potential retinal biomarkers were expressed by the normal mouse vitreous and retina. METHODS Vitreous and retina samples from mice were collected by evisceration and analyzed by...
The hamster suprachiasmatic nucleus (SCN), site of the circadian clock, has been thought to be equally and completely innervated by each retina. This issue was studied in animals that had received an injection of the tracer cholera toxin subunit B (CTb) conjugated to Alexa 488 into the vitreous of one eye, with CTb-Alexa 594 injected into the other. Retinal projections to the SCN and other nucl...
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