Long-term restriction of energy intake without malnutrition is a robust intervention that has been shown to prolong life and delay age-related morbidity. A 1H NMR-based metabonomic strategy was used to monitor urinary metabolic profiles throughout the lifetimes of control-fed and diet-restricted dogs. Urinary metabolic trajectories were constructed for each dog, and metabolic variation was foun...

Landscape features such as mountains, rivers, and ecological gradients may strongly affect patterns of dispersal and gene flow among populations and thereby shape population dynamics and evolutionary trajectories. The landscape may have a particularly strong effect on patterns of dispersal and gene flow in amphibians because amphibians are thought to have poor dispersal abilities. We examined g...

Clines in phenotypic traits with an underlying genetic basis potentially implicate natural selection. However, neutral evolutionary processes such as random colonization, spatially restricted gene flow, and genetic drift could also result in similar spatial patterns, especially for single-locus traits because of their susceptibility to stochastic events. One way to distinguish between adaptive ...

A review and reappraisal of bats of the genus Eumops (Chiroptera: Molossidae) reveals that considerable geographic variation is present in the bonneted bat, E. glaucinus; it is a complex consisting of .1 species. Bonneted bats in Florida are significantly larger than those in all other populations, and have proportionally shorter and deeper basisphenoid pits, the glenoid fossa is broadly triang...

Landscape features such as mountains, rivers, and ecological gradients may strongly affect patterns of dispersal and gene flow among populations and thereby shape population dynamics and evolutionary trajectories. The landscape may have a particularly strong effect on patterns of dispersal and gene flow in amphibians because amphibians are thought to have poor dispersal abilities. We examined g...

The relationship between the number of withdrawn/restricted drugs and socioeconomic, health, and welfare indicators were investigated in a comprehensive review of drug regulation information in the United Nations (UN) countries. A total of of 362 drugs were withdrawn and 248 were restricted during 1950-2010, corresponding to rates of 12.02 ± 13.07 and 5.77 ± 8.69 (mean ± SD), respectively, amon...

This paper discusses degree achievements cross-linguistically, focusing on the maximalization possibilities reported in literature. I introduce a four-way typology where languages differ regarding whether they overtly mark (with lexical items) (i.e., scale of achievement is bounded an event) and/ or event there unique maximal denotation predicate), and account for variation. The four types are ...

A stochastic model is developed for competition among organisms living in a patchy and varying environment. The model is designed to be suitable for species with sedentary adults and widely dispersing larvae or propagules, and applies best to marine systems but may also be adequate for some terrestrial systems. Three kinds of environmental variation are incorporated simultaneously in the model....