objectives we assessed the prevalence of three common viruses including; respiratory syncytial virus (rsv), human rhinovirus (hrv), and human metapneumovirus (hmpv), in children with acute wheezing. patients and methods ninety six wheezy children, 48 males (50%) and 48 females (50%)under the age of 5 years, were enrolled in the study. all patients visited as outpatients or inpatients when refer...

Methods have been developedto isolatemitochondriafrom small amounts of normal and leukemic human lymphocytes obtained from small volumes of circulating blood. Mitochondrial respiratory functions were measured by polarographic tech niques, and active calcium uptake was measured by a spectro photometric procedure utilizing the calcium-sensitive dye mu rexide. The results indicate that the rates o...

A BSTRACT Background Traditional approaches to mechanical ventilation use tidal volumes of 10 to 15 ml per kilogram of body weight and may cause stretch-induced lung injury in patients with acute lung injury and the acute respiratory distress syndrome. We therefore conducted a trial to determine whether ventilation with lower tidal volumes would improve the clinical outcomes in these patients. ...

BACKGROUND Measurements of maximal voluntary inspiratory (PI(max)) and expiratory (PE(max)) pressures are used in the management of respiratory muscle disease. There is little data on the appropriate reference range, success rates, or repeatability of PI(max) and PE(max) in children or on methodological factors affecting test outcomes. OBJECTIVES To determine PI(max) and PE(max) in healthy ch...

BACKGROUND Multiple rib fractures cause significant pain and potential for chest wall instability. Despite an emerging trend of surgical management of flail chest injuries, there are no studies examining the effect of rib fracture fixation on respiratory function. OBJECTIVES Using a novel full thorax human cadaveric breathing model, we sought to explore the effect of flail chest injury and su...

Maximal static inspiratory and expiratory mouth pressures (PI,max and PE,max, respectively) enable the noninvasive measurement of global respiratory muscle strength. The aim of this study was primarily to obtain normal values of PI,max and PE,max for adult Chinese, Malays and Indians and, secondarily, to study their effect on lung volumes in these subjects. Four hundred and fifty two healthy su...

BACKGROUND Chest wall mobility is often measured in clinical practice, but the correlations between chest wall mobility and respiratory muscle strength and lung volumes are unknown. We investigate the associations between chest wall mobility, axillary and thoracic cirtometry values, respiratory muscle strength (maximum inspiratory pressure and maximum expiratory pressure), and lung volumes (exp...

Sound production during trumpet playing implies the interaction between the performer and his instrument which requires the coordination between physiological and physical parameters under the performer's direct control. For brass instruments, some of the main issues rely on the estimation of specific parameters such as mouth pressure, lip mechanical properties and driving volume flow. A few st...

Accurate patient state assessments from the interpretation of noisy physiological time-series data are important in patient monitoring in critical care medicine. Given the large volumes of respiratory signal data originating from multiple monitoring devices in the Intensive Care Unit (ICU), we believe it is better to convert this data into trends that have abstractions increasing, decreasing or...

OBJECTIVE To describe the incidence and main clinical characteristics of barotrauma during open lung ventilation (OLV). DESIGN A retrospective, observational, descriptive study was made of 100 patients with acute respiratory failure and bilateral pulmonary infiltrates. INTERVENTIONS 1) A lung recruitment maneuver (LRM) with fixed ventilation pressure and progressive positive end-expiratory ...