Anemia is a common complication in hemodialysis (HD) patients, mainly due to the insuffi‐ cient production of erythropoietin (EPO) by the failing kidneys [1]. Anemia itself can worsens cardiac function, cognitive function, exercise capacity and quality of life, and it has been independently associated with increased mortality and progression of renal disease [2, 3]. A successful management of a...

McCommis KS, McGee AM, Laughlin MH, Bowles DK, Baines CP. Hypercholesterolemia increases mitochondrial oxidative stress and enhances the MPT response in the porcine myocardium: beneficial effects of chronic exercise. Am J Physiol Regul Integr Comp Physiol 301: R1250–R1258, 2011. First published August 24, 2011; doi:10.1152/ajpregu.00841.2010.—Hypercholesterolemia has been suggested to have dire...

Regular exercise plays an important preventive and therapeutic role in oxidative stress-associated diseases such as diabetes and its complications. Thiol antioxidants including thioredoxin (TRX) and glutathione (GSH) have a crucial role in controlling cellular redox status. In this study, the effects of 8 wk of exercise training on brain TRX and GSH systems, and antioxidant enzymes were tested ...

Cellular expression of host prion protein (PrP) is essential to infection with prion disease. Understanding the mechanisms that regulate prion protein expression at both the transcriptional and translational levels is therefore an important goal. The cellular prion protein has been associated with resistance to oxidative, and its expression is also increased by oxidative stress. The transcripti...

cirrhosis is associated with hyperdynamic circulation, manifesting as increased cardiac output and decreased systemic vascular resistance. the aim of this study was to investigate the effect of cirrhosis on heart apoptosis and involvement of nitric oxide (no) and oxidative stress in the possible altered apoptosis of cirrhotic hearts. twenty-eight days after bile duct ligation, heart tissues wer...

purpose prolonged physical exercise results in transient elevations of biochemical markers of muscular damage. this study examined the effect of short-term maximal exercise on these markers, homocysteine levels (hcy), and total antioxidant status (tas) in trained subjects. methods eighteen male football players participated in this study. blood samples were collected 5-min before and 3-min afte...

Background. Adipose tissue secrets various hormones in body such as adiponectin which has close relationship with controlling weight. Objectives. Therefore, the present article determines movement pattern effect of resistance training on adiponectin, in young men. Methods. 40 male untrained students in 23.8±2.66 years old and weight of 67.43±4.96 kg were randomly selected,...

It has been shown that exercise is helpful against brain disorders. However, this may not be true for intense exercise (IE). Because it is easy to misadjust exercise intensity with physical condition, it is essential to know the effects of IE on cognitive process because it may have important consequences on people skills and work skills. We investigated the effects of IE on male C57Bl/6 mice, ...