a topical o/w cream containing tretinoin microspheres was prepared. gelatin microspheres of tretinoin were prepared using coacervation method. these microspheres contained about 50% w/w tretinoin. the particle size range of microspheres was between 90-150 m m. in vitro drug release from microspheres and a cream formulation was studied. it was shown that drug release from microspheres followed h...

In this paper, we are interested in parallel identical machine scheduling problems with preemption and release dates in case of a regular criterion to be minimized. We show that solutions having a permutation flow shop structure are dominant if there exists an optimal solution with completion times scheduled in the same order as the release dates, or if there is no release date. We also prove t...

1 Department of Computer Science University for Development Studies, Ghana 2 Department of Industrial and Production Engineering University of Ibadan, Nigeria Corresponding Author: E. O. Oyetunji _________________________________________________________________________________________________ Abstract This paper considers the scheduling problem of simultaneously minimizing the makespan and tota...

OBJECTIVE To evaluate the impact of methadone dose on post-release retention in treatment among HIV-infected prisoners initiating methadone maintenance treatment (MMT) within prison. METHODS Thirty HIV-infected prisoners meeting DSM-IV pre-incarceration criteria for opioid dependence were enrolled in a prison-based, pre-release MMT program in Klang Valley, Malaysia; 3 died before release from...

Storm water detention has been widely used for on-site runoff release control. The required storm water detention volumes are often determined by the pre-selected release rates for various design events. When a low release rate is selected, the basin stores more storm water volume than required and it results in an insufficient base flow for the downstream habitats. When a high release is selec...

Study Design Retrospective case series from one institution with a comparison control group. Objective To evaluate the safety of concomitant tethered cord release and growing-rod insertion in individuals with early onset scoliosis. Methods We retrospectively reviewed patients who underwent concurrent tethered cord release and growing-rod insertion. We compared our data to a comparison control g...

Study objectives: Comparison of efficacy of Myofascial release and positional release therapy in tension type headache. Design: Comparative study. Setting: All the subjects were included from various clinics, hospitals and community in dehradun. Method: Total of 28 subjects was recruited for study on the basis of inclusion and exclusion criteria after signing the informed consent form. Subjects...

previous studies have reported the efficacy of baclofen in the treatment of gastroesophageal reflux diseases (gerd). the objective of present study is to evaluate the effect of co-administration of omeprazole 20 mg/d plus sustained release baclofen (sr baclofen) vs omeprazole 20 mg/d plus placebo on alleviation of symptoms in patients with a diagnosis of gerd. a prospective, double blind, place...

Objective: This study aims to find and compare the effects of primal reflex release technique and stretching exercises on pain intensity, functional performance, and pain-free sitting duration in patients with coccydynia. Methods: This is a randomized clinical trial. A total of 46 individuals were chosen for the sample based on the inclusion criteria, and they were divided into groups A and B....