Pregnancy-related liver disorders accounted for 8% of all maternal deaths at our center from 1999 to 2011. Of the three pregnancy-related liver disorders (acute fatty liver of pregnancy (AFLP), HELLP (Hemolysis, elevated liver enzymes, low platelets) syndrome and pre-eclamptic liver dysfunction, which can lead to adverse maternal and fetal outcome, AFLP is most typically under - diagnosed. Risk...

Dysmenorrhea is a common symptom secondary to various gynecological disorders, but it is also represented in most women as a primary form of disease. Pain associated with dysmenorrhea is caused by hypersecretion of prostaglandins and an increased uterine contractility. The primary dysmenorrhea is quite frequent in young women and remains with a good prognosis, even though it is associated with ...

Patients with Huntington’s disease (HD) have been shown to exhibit impairment in the recognition of facial expressions such as disgust, as well as deficits in disgust responses to olfactory and gustatory stimuli. The present study investigated whether HD is associated with changes in emotional responses to a variety of visual and verbal stimuli selected to elicit core disgust, moral disgust, fe...

The consumption of a wide variety of substances determines, through different mechanisms, the onset of sleep disturbances, which has a considerable impact on the neurobiology of sleep-wake circadian rhythm. Many substances are widely used and easy to find, such as alcohol, nicotine and caffeine and are frequently the cause of degradation in quality and quantity of sleep. Furthermore, substance ...

Gluten associated disorders and the question around these associations has recently attracted attentions of many health professionals. This is because of high prevalence of undiagnosed gluten related disorders presenting with a multitude of symptoms and complications inside and outside small bowel. While the environmental factors associated with a complex genetics are leading to destructions of...

Background: Retrospective studies suggest that many Parkinson’s disease patients have a worsening of their motor status during hospitalization. We aimed to quantify this prospectively, and study possible contributing factors. Methods: Over one year we included all consecutive Parkinson’s disease patients, newly admitted to a Dutch teaching hospital. We analyzed complications, interventions, and...

Sleep disorders encompass a broad group of conditions. In this article the sleep related breathing disorders are considered from the initial presentation through diagnosis and investigations to management.