نتایج جستجو برای: related apoptosis

تعداد نتایج: 1304336  

Objective(s): Activation of acid-sensing ion channel 1a (ASIC1a) is responsible for tissue injury caused by acidosis in nervous systems. But its physiological and pathological roles in nucleus pulposus cells (NPCs) are unclear. The aim of this study is to investigate whether ASIC1a regulates the survival of NPCs in the acidic environment of degenerated discs. Materials and Methods: NPCs were i...

Journal: :iranian journal of pharmaceutical research 0
yong peng yanshan university zhan-zhao fu the first hospital of qinhuangdao town cong-shan guo yanshan university yan-xia zhang yanshan university bin jiang yanshan university bin jiang yanshan university

the objective of this study was to observe the apoptosis-inducing effect and mechanism of baicalin on human cervical cancer hela cells. the inhibitory effect of baicalin on the growth of hela cells was measured by mtt assay, and cell proliferation and migration was analyzed by cell scratch assay. morphological changes of apoptotic cells were viewed by the light microscope and electron microscop...

Journal: :progress in biological sciences 2011
hossein ghamartaj manijeh khanmohammadi neda jarooghi somaye kazemnejad

the association of secreted frizzled related protein type 4 (sfrp4) as an antagonist of wnt mole-cules in apoptotic events has been reported previously. moreover, its increased expression has been reported in the ovary of women with polycystic ovary (pco). we have demonstrated in-creased sfrp4 in pco-induced rat ovary related to an increased number of apoptotic follicles showing nuclear ?cateni...

Journal: :Indian Journal of Pharmaceutical Sciences 2022

Ewing sarcoma is the second most common primary malignant bone tumor in pediatrics after osteosarcoma, which mainly occurs children and adolescents aged 5-20 y. Crocin main active ingredient extracted from Crocus sativus has significant inhibitory effect on many cancer cells. Therefore, this study observed of crocin human its specific mechanism provided molecular theoretical basis for clinical ...

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