Background. The practice of OPAT became widespread with demonstration of its safety in selected patients. However, with concerted efforts to reduce hospital lengths of stay, there is currently no selection for OPAT. Virtually every patient is a potential candidate for OPAT. Data on OPAT outcomes with unselected patients are very limited. The purpose of this study was to evaluate clinical outcom...

11. Wallace AM, McMahon AD, Packard CJ et al. Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS). Circulation 2001; 104: 3052–6. 12. van den Beld AW, Bots ML, Janssen JA et al. Endogenous hormones and carotid atherosclerosis in elderly men. Am J Epidemiol 2003; 157: 25–31. 13. Zung A. A self-rating depression scale. Arch Gen Psychiat...

of Beltz et al., in this issue). The present study on Carcinus established that semi-isolated crab brain preparations, perfused at rates as low as 0.45ml/min and at room temperature, remain physiologically active for 6 hours or more. This was confirmed by stimulating the nerve root carrying afferent information from tactile receptors around the eyes to the brain, which results in a reflexive wi...

Background. OPAT is commonly administered at home. Such treatment has potential for the occurrence of antimicrobial adverse events (AEs) and vascular access complications that require clinical intervention. The purpose of this study was to examine adverse events and complications that occur during the course of OPAT at home. Methods. All OPAT courses carried out at home for patients at Clevelan...

In “The Case for a Heroin Substitution Treatment Trial in Canada,” Fischer and Rehm conclude that such a trial is timely, if not long overdue; that there is sufficient evidence both in theory and practice to support such an initiative; and that there is both need and opportunity for improved effectiveness in Canadian opiate substitution policy. In particular, they conclude that there is an urge...

Heritability of resistance to gummy stem blight (Didymella bryoniae (Auersw.) Rehm.) was measured in two diverse cucumber (Cucumis sativus L.) populations [North Carolina elite slicer 1 (NCES1) and North Carolina wide base pickle (NCWBP)]. Heritability was estimated using parent–offspring regression and half-sib family analysis in North Carolina field tests during 1991 and 1992. NCES1 is a slic...

Recommendations for applying nitrogen (N) fertilizer in autumn involve delaying applications until daily soil temperature at 10-cm depth is #10 C. Daily soil temperature data during autumn were examined from 26 sites along a transect from 36 to 49 N latitude in mid-continent USA. After soils first cooled to #10 C (First10), temperatures usually rebounded for varying amounts of time before the f...

Leaf and stem resistance to gummy stem blight [Didymella bryoniae (Auersw.) Rehm.] in five resistant by susceptible crosses of cucumber (Cucumis sativus L.) was investigated using generation means analysis. No single gene of major effect controls either leaf or stem resistance to gummy stem blight in these five crosses. The mean number of effective factors controlling leaf resistance in the cro...