نتایج جستجو برای: regulated and 69 down

تعداد نتایج: 16868431  

2013
Takahide Hayano Manoj Garg Dong Yin Makoto Sudo Norihiko Kawamata Shuo Shi Wenwen Chien Ling-wen Ding Geraldine Leong Seiichi Mori Dong Xie Patrick Tan H Phillip Koeffler

BACKGROUND SOX7 is a transcription factor belonging to the SOX family. Its role in lung cancer is unknown. METHODS In this study, whole genomic copy number analysis was performed on a series of non-small cell lung cancer (NSCLC) cell lines and samples from individuals with epidermal growth factor receptor (EGFR) mutations using a SNP-Chip platform. SOX7 was measured in NSCLC samples and cell ...

Journal: :Chemical communications 2011
Keisuke Okada Mahasweta Nandi Jun Maruyama Tatsuya Oka Takashi Tsujimoto Katsuyoshi Kondoh Hiroshi Uyama

Mesoporous polyacrylonitrile (PAN) monolith has been fabricated by a template-free approach using the unique affinity of PAN towards a water/dimethyl sulfoxide (DMSO) mixture. A newly developed Thermally Induced Phase Separation Technique (TIPS) has been used to obtain the polymer monoliths and their microstructures have been controlled by optimizing the concentration and cooling temperature.

Background: Colorectal cancer (CRC) is one of the most common causes of cancer-related death in the world. The expression of N-myc downstream-regulated gene 2 (NDRG2) is down-regulated in CRC. The aim of this study was to investigate the effect of NDRG2 overexpression on cell proliferation and invasive potential of SW48 cells.Methods: SW48 cells were transfected with a plasmid overexpressing ND...

Tahereh Foroutan,

Bachgroun: Hematopoietic stem cell derived from umbilical cord blood (UCB) has been used for regenerative medicine in hematological abnormalities. MicroRNAs are important regulators of gene expression that control both physiological and pathological processes such as development of tissue and cancer. Some studies have shown that miR-33, has a critical role in control of self-renewal cells. He...

Journal: :genetics in the 3rd millennium 0
zahrasadat hosseini mohammad tahmaseb masoud houshmand sahel hemmati arvin haghighatfard

schizophrenia (scz) is a complex disorder with no clarified etiology or biological diagnosis.  symptoms of schizophrenia including positive, negative and cognitive deficits.the neurodegenrative and neurodevelopmental hypothesis are main views  about the pathophysiology of schizophrenia. neuregulin 1 is one of four proteins in the neuregulin family that act on the egfr family of receptors. nrg1 ...

Journal: :iranian journal of medical sciences 0
a. kariminia b. gharegozloo s. k. ardestani

background: despite demonstration of molecular and biochemical changes induced by heat shock on leishmania , the immunological importance of such changes has not been elucidated.   objective: studying the effect of two excretory factors prepared under heat shock and ambient temperature from leishmania major on balb/c splenocytes function.   methods: the parasites were cultured at 25 ° c and the...

Journal: :iranian journal of medical sciences 0
amaneh mohammadi roushandeh raheleh halabian parisa mozafari jafar soleimani rad behnaz sadeghzadeh oskouei ali samadi kuchaksaraei

background: the effects of electromagnetic field (emf) on reproductive system have been of critical concern for a long time. it has been shown that the emf can adversely affect testicular cells and tissue and decrease male fertility. the most important determinants of male fertility are sperm development and motility, which are affected by changes in several factors including lipocalin 2 protei...

Background and Aims: Substantial damage to the kidney tissue and diabetic nephropathy (DN) can be caused by chronic hyperglycemic conditions and exposure to a high level of blood glucose. In the current study, we explored the capability of adipose-derived mesenchymal stem cells (ADSCs) and Toll-like receptor-4-primed mesenchymal stem cells (TLR4-primed MSCs) on kidney regeneration, resolution ...

Journal: :Journal of Experimental & Clinical Cancer Research 2009

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