A highly regioselective protocol for the direct synthesis of γ,δ-unsaturated ketones from β-ketoacids and allylic alcohols was proposed and accomplished relying on the combination of [Ir(cod)Cl]2 and 10-camphorsulfonic acid via decarboxylative allylation.

In the RuCl2(p-cymene)/PPh3 catalysed regioselective allylic alkylation of monosubstituted allyl acetates with malonate anion, the selective substitution at the position originally substituted with acetate was observed.

Regioselective [2+2] cycloaddition of ynones or ynoates to siloxy(trialkoxy)ethene (KSA) is described. A siloxy group on the KSA directs the perfect regioselectivity, allowing rapid construction of various functionalized cyclobutenedione derivatives.

Combining CO 2 and H for chemo- regioselective hydroformylation of alkenes has been realized. The key to success is the use a bifunctional Rh/PTA catalyst, which can ingeniously combine efficient hydrogenation hydroformylation.

Protein engineering of an unspecific peroxygenase (UPO) was performed with three substrates and six products in parallel by a high throughput GC-MS setup. Modified chemo- regioselective variants were identified for aliphatic substrates.

A C–N bond formation reaction under benign conditions for the amination of allenic ketones to access enaminones is reported. This atom economical, green, highly regioselective and works well with many structurally crucial amines.

Organoimidoylization of Polyoxometalates (POMs) can dramatically modify the electronic structures of POMs and gives rise to novel "value-adding" properties of the POMs for promising material applications including photo-electronic transformation and catalysis. To date, the preparation of multi-functionalized organoimido derivatives of POMs is generally conducted under strict condition and is ti...

Article history: Received 22 August 2016 Received in revised form 7 October 2016 Accepted 23 October 2016 Available online 24 October 2016 An efficient glucosylation of alcoholic hydroxyls in the structures of protostane triterpenoids catalyzed by fungus has been developed. Four protostanes 1–4 as the substrates have been transformed by Syncephalastrum racemosumAS 3.264 and generated correspond...

The regioselective synthesis of several quercetin (3,3',4',5,7-pentahydroxy flavone) tetraesters bearing a single free OH on 5-C was achieved in good yield by proper choice of reaction conditions using common esterification procedures. Tetracetylated quercetin with the free OH on 7-C was selectively obtained instead via imidazole-promoted deacylation of the corresponding pentaester. Unambiguous...