Background & Aims: Considering increasing incidence of cardiovascular disorders in diabetes mellitus and some evidence on antioxidant and antidiabetic potentials of naringenin, this study was conducted to evaluate the beneficial effects of 6-week administration of naringenin on contractile reactivity of isolated thoracic aorta in diabetic rats. Methods: Male Wistar rats were divided into contro...

Inhalational insulin was withdrawn from the market due to its potential to produce airway hyper-reactivity and bronchoconstriction. So the present study was designed to explore the acute effects of insulin on airway reactivity of guinea pigs and protective effects of salbutamol and beclomethasone against insulin induced airway hyper-responsiveness on isolated tracheal smooth muscle of guinea pi...

 Abstract Background: Dysfunction of the autonomic nervous system has long been a subject of considerable debate and a large number of studies have disclosed contradictory results. The aim of this study was to compare cerebral vasomotor reactivity in migraine with aura (MWA) patients with migraine without aura (MWO) ones. Methods: Ten MWA patients (7 females and 3 males mean age: 39.70 years, S...

The purpose of the present research work is prediction of electronic and physico-chemical properties of the novel medicinal compound Ticagrelor (AZD6140) using density functional theory (DFT) method. Firstly, its molecular structure was optimized at B3LYP/6-311++G(d,p) basis set of theory at room temperature. The global reactivity indices used to study the reactivity and stability of the title ...

This study examined the association between cardiovascular reactivity and proactive and reactive functions of relational aggression among women with and without a history of sexual abuse. Heart rate reactivity, blood pressure reactivity, and respiratory sinus arrhythmia reactivity while recounting a relational stressor (e.g., being left out) were assessed. Participants provided self-reports of ...

The morpholinium cation based ionic liquids are designed to evaluate the thermophysical, chemical reactivity, and biological activity. To estimate and design the bioactive ILs, propionate and trihalopropanoate were considered under theoretical study by Density Functional Theory (DFT). To make effect of halogens atom on anion, propionate, trifluro propionate, trichloro propionate, and tribromo p...

Inhalational insulin was withdrawn from the market due to its potential to produce airway hyper-reactivity and bronchoconstriction. So the present study was designed to explore the acute effects of insulin on airway reactivity of guinea pigs and protective effects of salbutamol and beclomethasone against insulin induced airway hyper-responsiveness on isolated tracheal smooth muscle of guinea pi...

Background & Aims: Considering the higher incidence of cardiovascular disorders in diabetes mellitus and some evidence on antioxidant and antidiabetic potential of Tribulus terrestris (TT), this study was conducted to evaluate the beneficial effect of 6-week oral administration of TT on contractile reactivity of isolated thoracic aorta in diabetic rats. Methods: Female Wistar rats were divided ...

The morpholinium cation based ionic liquids are designed to evaluate the thermophysical, chemical reactivity, and biological activity. To estimate and design the bioactive ILs, propionate and trihalopropanoate were considered under theoretical study by Density Functional Theory (DFT). To make effect of halogens atom on anion, propionate, trifluro propionate, trichloro propionate, and tribromo p...