Objective: Cytokeratins are epithelium-specific intermediate filaments. Their altered expression is evident in various benign, hyperplastic and neoplastic lesions. This review provides an in-depth description of cytokeratin expression patterns in odontogenesis; normal development, hyperplastic/benign and malignant lesions or conditions. Materials and methods: Cytokeratin expression can be studi...

BACKGROUND AND AIM: Oral and maxillofacial lesions vary in different geographic regions based on their clinical features. Until now, few investigations have studied these lesions in children and adolescents in Iran. The aim of this research was to study the clinicopathological manifestations of biopsied oral and maxillofacial lesions among children and adolescents in the south of Iran.METHODS: ...

Atypical fowlpox occurred in several poultry farms in Kenya. On two occasions layers had their eyes closed and egg production dropped. Fowlpox virus was isolated from lesions on the inner surfaces of the closed eyelids. Other chickens had lesions covered by yellow caseous necrotic material in the mouth, around the epiglottis, and in the trachea and choanae. Typical proliferative cutaneous lesio...

introduction the frequency of pediatric and adolescent oral and maxillofacial lesions is various in different societies. the present study aimed at investigating the frequency of oral and maxillofacial pediatric and adolescent biopsies in zahedan (southeast iran), and compare the results with other epidemiologic studies.methods and materials this retrospective study reviewed oral and maxillofac...

The morphogenesis of 1, 2-dimethylhydrazine (DMH)-induced lesions in the colon of outbred NIH Swiss mice was determined for up to 5 months of treatment. The effect of hyperplasia on DMH carcinogenesis was also evaluated by introducing a transient hyperplastic stimulus to the colon during the chronic weekly treatment regimen of DMH. The hyperplastic stimulus was a naturally occurring disease of ...

Hepatic abnormalities are described in three patients who received synthetic anabolic steroids. A child with Franconi's anaemia was treated for four years and at necropsy the liver showed generalized hyperplasia, hyperplastic nodules, and a benign hepatoma. Two adults received only three months' therapy with synthetic androgens; in one there was generalized hepatic hyperplasia and in the other ...

pyogenic granuloma (pg) is a reactive inflammatory hyperplastic oral lesion in response to local irritants. it is the most commonly occurring and a well-known oral lesion by oral physicians that most commonly affects gingiva, followed by lips, buccal mucosa, palate and tongue. “pyogenic granuloma” term itself is a misnomer. this article presents a report of 2 cases of pyogenic granuloma of ...

Carcinogenesis is believed to be a multi-step process, progressing sequentially from normal to hyperplastic, to in situ, and to invasive stages. A number of studies, however, have detected malignancy-associated alterations in normal or hyperplastic tissues. As the molecular profile and clinical features of these tissues have not been defined, the authors invited several well-recognized patholog...

BACKGROUND Gastric cancer is one of the most frequent malignancies in the world, ranking fifth in the Netherlands as a cause of cancer death. Surgery is the only curative treatment for advanced cases, but results of gastrectomy largely depend on the stage of the disease. A better understanding of the mechanisms of progression from a preneoplastic condition through intraepithelial neoplasia to i...