Abstract Superparamagnetic Iron Oxide Nanoparticles (SPIONs) are more and used in biomedical applications such as therapy (treatment for certain cancers, hyperthermia), diagnostic (contrast agent Magnetic Resonance Imaging) or both. For these applications, SPIONs must be stable an aqueous solution, monodisperse, with a narrow size distribution without aggregation. To obtain nanoparticles, micro...