Clinical practice guidelines (CPGs) have been developed to summarize evidence about the management of rheumatoid arthritis (RA) and facilitate the uptake of evidence-based knowledge by consumers, health professionals, health administrators and policy makers. The objectives of this review was to assess the quality of CPGS on non-pharmacological management of RA with a standardized and validated ...

introduction: appraiser is the main interface between the performance appraisal system and those being appraised. their views and behaviors have different effects on the performance of the evaluation system, as well as the reactions subjects of the appraisal make toward the system and their subsequent performance. hence, appraisers need to be trained enough regarding the appraisal. therefore, t...

The recombinant interleukin-1 receptor antagonist, anakinra (Kineret; Amgen Inc., Thousand Oaks, CA), has been approved by the US Food and Drug Administration and the European Commission for the treatment of patients with active rheumatoid arthritis (RA). Approval was granted following the extensive evaluation of anakinra in five pivotal clinical trials that assessed its efficacy and safety in ...

Treatment of rheumatoid arthritis (RA) with biological disease-modifying anti-rheumatic drugs (bDMARDs) induces rapid remission. However, osteoporosis and its management remains a problem. The Geriatric Nutritional Risk Index (GNRI) evaluates the risk of malnutrition-related complications in elderly patients and has been shown to be a significant predictor of many diseases. We evaluated the cor...

Cells of OS2-RA, a human small cell lung cancer line sensitive to lymphokine-activated killer (LAK) cells, were repeatedly cocultured with human LAK cells. Fourteen cycles of the coculture produced a variant, termed OS2-RA-R, capable of growing successfully in the presence of LAK cells. OS2-RA-R showed a moderate resistance to lysis by LAK cells in 4-h 51Cr release assays. OS2-RA-R acted positi...

background: rheumatoid arthritis (ra) is a chronic inflammatory disease with many genetic factors predisposing to disease susceptibility. the aim of the present study was to investigate the impact of cd226 rs727088 and rs763361 polymorphisms and susceptibility to ra in a sample of the iranian population. methods: this case-control study was carried out on 100 patients with ra and 104 healthy su...

Glucocorticoids are given during pregnancy when rheumatoid arthritis (RA) is too active. It could lead to increased risk of cardiovascular diseases (CVD) and type 2 diabetes mellitus (T2DM) in the offspring. Elevated RA disease activity during pregnancy is associated with low birth weight and rapid post-natal growth. Both can negatively influence the body composition later in life. This study s...

Multi-FPGA boards are being used for logic emulation, rapid prototyping, custom computing and low volume subsystem implementation. A key feature which characterizes these boards is their routing architecture(RA). Inter-FPGA connections in an RA can be of two types, namely fixed connections through direct wires and programmable connections through intermediate Field-Programmable Interconnect Dev...

Rheumatoid arthritis (RA) is an incurable chronic inflammatory disease associated with significant functional impairment and disability, linked to inflammatory and structural articular and peri-articular damage. Structural damage occurs rapidly in RA if inflammation is not efficiently suppressed. Identification of patients with high risk to develop RA followed by an early application of efficie...