This study is aimed to evaluate the effects of setup errors on dose distribution for target volume and healthy tissue within the irradiated volume and also critical surrounding organs for breast radiotherapy (RT) using both the tangential field and the field-in-field (FIF) technique. Ten patients with breast cancer were enrolled. For each patients two plans were generated; tangential field plan...

A prostate treatment immobilization system was evaluated with respect to setup errors and efficiency for a specific treatment setup. Prostate patients were treated in the prone position with a rectal catheter using the NOMOS intensity modulated radiotherapy system. Immobilization and setup consisted of a Vac-Loktrade mark bag (MED-TEC, Orange City, IO) fitted within a registration carrier box w...

BACKGROUND The purpose of this clinical study is to investigate the clinical feasibility and safety of a shuttle-based MR-linac connection to provide MR-guided radiotherapy. METHODS/DESIGN A total of 40 patients with an indication for a neoadjuvant, adjuvant or definitive radiation treatment will be recruited including tumors of the head and neck region, thorax, upper gastrointestinal tract a...

Recent linear accelerators can perform cone-beam computed tomography to correct setup errors immediately before dose delivery. We calculated the dose distribution with setup errors acquired from cone-beam computed tomography to determine a more realistic and individual effect of setup errors. The differences in dose distribution were analyzed. The setup errors of three patients who were irradia...

Abstract Cancer prevention and treatment are currently the focus of most research. Dose verification is an important step for reducing improper dose deposition during radiotherapy. To mend traditional gel dosimeters 3D verification, a novel rare-earth nanoparticle-based composite was prepared, which has good radioluminescence property reusability. It promising phantom material new dosimeter. TE...

Accident analysis in radiotherapy highlighted the need to increase quality assurance (QA) programs by identification of failures/errors with very low probability (rare event) but severe consequences. In this field, a Failure Mode, Effects and Criticality Analysis (FMECA) technique, used various industrial processes rank critical events, has been met much interest. The literature describes diffe...

Radiotherapy treatment is often delivered in a fractionated manner over a period of time. Emerging delivery devices are able to determine the actual dose that has been delivered at each stage facilitating the use of adaptive treatment plans that compensate for errors in delivery. We formulate a model of the day-to-day planning problem as a stochastic program and exhibit the gains that can be ac...

Background The superior soft tissue contrast of magnetic resonance imaging (MRI) compared to computed tomography (CT) has urged the integration of MRI and exclusion of CT in prostate radiotherapy treatment, referred to as an MRI-only workflow. Such a workflow can eliminate image registration errors between the CTand MR-images but incorporates multiple challenges. MR-images lack electron density...