the purpose of the research was determine the effects of gamma ray on seed germination, seedling height and root length of rice (oryza sativa l. spp. indica cv. mr219) to identify the lethal dosage of the radiation. paddy seeds of mr219 were exposed to different doses of gamma radiations viz 50,100,150,200,250,300,350,400,450,500,600,700,800,900 and 1000 gy using 60co as the radiation source. t...

The Rothmund–Thomson syndrome (RTS) is a rare autosomal recessive disease associated with poikiloderma, telangiectasias, sun-sensitive rash, hair growth problems, juvenile cataracts and, for subset of some RTS patients, high risk cancer, especially osteosarcoma. Most the cases are caused by biallelic mutations RECQL4 gene, coding DNA helicase that belongs to RecQ family. Cellular and post-radio...

Radiations in medicine cover a wide range of applications, predominantly diagnostic imaging and radiotherapy, encompassing photons (x- γ-rays) particle radiation, as well with the use liquid sources nuclear focusing on physiological functional imaging, tumour detection or targeted radiotherapy. The biological interactions ionizing radiation leads naturally to questions benefits risk following d...

BACKGROUND Radiation is an effective treatment against nasopharyngeal carcinoma (NPC). However, radioresistance-induced locoregional recurrence remains as a major cause of treatment failure. Therefore, radiosensitivity indicators prior to treatment should be developed to screen radioresistant patients. Previous studies revealed that RKIP (Raf kinase inhibitor protein) is associated with NPC pro...

Background and purpose: Individual radiosensitivity is an inherent characteristic, associated with an increased reaction to ionizing radiation on the human body. Individuals show marked differences in radiation sensitivity, which has consequences in the fields of both radiation protection and radiation therapy. It is suggested that DNA repair mechanisms are involved. Consequently, the character...

There are contradictory observations about the different radiosensitivities of cancer stem cells and cancer non-stem cells. To resolve these contradictory observations, we studied radiosensitivities by employing breast cancer stem cell (CSC)-like MDAMB231 and MDA-MB453 cells as well as their corresponding non-stem cells. CSC-like cells proliferate without differentiating and have characteristic...

Most studies of radioadaptive response (RAR) in vivo have revealed its effective induction both by chronic and single irradiation a human organism with low doses. The classical way the for-mation RAR on peripheral blood lymphocytes (PBL) was noted as occupationally irradiated personnel residents areas increased natural or man-made accidental high background radiation. In some studies, liquidato...

Low dose radiosensitivity of in vitro generated alloimmune murine cytotoxic T lymphocytes (CTL) was studied. It appears that a subset of CTL exists that can be killed with 10-25 rad of x rays. These radiosensitive CTL are Lyt-1,2+ T lymphocytes. Analyses of cytotoxicity by chromium release assays indicate that the radiosensitive CTL are present in responder spleen cell cultures from all strains...