The antioxidant activity of C-Phycocyanin (C-PC) isolated from three cyanobacterial species Lyngbya (marine), Phormidium (marine) and Spirulina (fresh water) was studied in vitro. The results demonstrate that C-PCs from Lyngbya, Phormidium and Spirulina spp. are able to scavenge peroxyl radicals (determined by crocin bleaching assay) with relative rate constant ratio of 3.13, 1.89 and 1.8, resp...

Free radicals and reactive oxygen species are generated in the body due to various physiological and biochemical processes. They are responsible for various chronic diseases like cancer, diabetes and oxidative damage of DNA and proteins. There is a huge demand of herbal antioxidant compounds in the market. Padaeria foetida,Tribulus terrestris and Oxalis corniculata are used in traditional healt...

The stem bark of Enantia chlorantha is commonly used for the treatment of malaria and other ailments of the human body such as cough and wound. The plant had been intensely studied for its antimicrobial activities and antipyretic properties. However, the efficacy and mechanisms of action of the plant remain unclear. Therefore, the objective of the present study was to determine the in vitro ant...

Leucas linifolia belongs to the family Lamiaceae and is a well know traditional medicinal plant in India. It is an herbaceous annual weed. In ayurveda, it is used for the treatment of cough, cold, fever, loss of appetite, skin disease, head ache, jaundice, Snake bite and scorpion sting. It has shown hepato protective activity against dgalactosamine and CCl4 induced hepatotoxicity in rats. Metha...

Organic radicals are neutral, purely organic molecules exhibiting an intrinsic magnetic moment due to the presence of an unpaired electron in the molecule in its ground state. This property, added to the low spin-orbit coupling and weak hyperfine interactions, make neutral organic radicals good candidates for molecular spintronics insofar as the radical character is stable in solid state electr...

The present study was designed to evaluate and compare the phenolic (total phenols and flavonoid) contents and antioxidant activity of aqueous extract of Momordica foetida (AEMF) and ethanolic extract of Momordica foetida (EEMF) extract of Momordica foetida leaves; a popular medicinal plant used for traditional medicine preparations. The antioxidant activity of both extracts was assessed using ...

We have designed and synthesized DNA duplexes containing 5-dimethylaminocytosine ((DMA)C) to investigate the effects of C(5)-substituted cytosine bases on the transfer and trapping of positive charge (holes) in DNA duplexes. Fluorescence quenching experiments revealed that a (DMA)C base is more readily one-electron oxidized into a radical cation intermediate as compared with other natural nucle...

A quantitative structure-activity relationship (QSAR) study of the 2,2-diphenyl-l-picrylhydrazyl (DPPH•) radical scavenging ability of 1373 chemical compounds, using DRAGON molecular descriptors (MD) and the neural network technique, a technique based on the multilayer multilayer perceptron (MLP), was developed. The built model demonstrated a satisfactory performance for the training ( R 2 = 0....

Acute postoperative pain following radical mastectomy is a high risk for prolonged convalescence and potential persistent pain in patients with breast cancer. The present study was designed to observe the effect of intraoperative use of dexmedetomidine on acute postoperative pain following radical mastectomy under general anesthesia. Forty-five patients were enrolled into the study and divided ...

Vitamin C (VC) is a well-known antioxidant and strong free radical scavenger. Its antioxidant activity is useful for protection of cellular macromolecules, particularly DNA, from oxidative damage induced by different agents. This study was undertaken to evaluate the optimum level of VC in attenuating the chromosome aberrations (CAs) and DNA damage after iron sulfate (FeSO4) acute administration...