The aim of our study was to characterize the repolarization disorders propensity induced by drug-drug interaction. In this observational retrospective study, we report experience on all elderly patients with ascertained diagnosis coronavirus disease 2019 through nasopharyngeal swab real time-polymerase chain reaction at Pugliese-Ciaccio hospital in Catanzaro, who received hydroxychloroquine (HC...

Objective—To determine the normal values of QT and QTc dispersion and the eVects of sinus arrhythmia on QT dispersion in healthy children. Patients and setting—The study was carried out in a university hospital on 372 local schoolchildren (200 male, 172 female), aged seven to 18 years. Methods—The QT and preceding RR intervals of at least one sinus beat were measured manually in a range of nine...

BACKGROUND Several reports have demonstrated an association between psoriasis and cardiovascular diseases. P wave dispersion (PWD) is the most important electrocardiographic (ECG) markers used to evaluate the risk of atrial arrhythmias. QT dispersion (QTD) can be used to assess homogeneity of cardiac repolarization and may be a risk for ventricular arrhythmias. AIM To search PWD and QTD in pa...

background: qt interval parameters have been suggested as a predictor of lethal arrhythmia and mortality in patients with myocardial infarction. the aim of the present study was to compare the value of qt interval indices in patients presenting with non-st-segment elevation myocardial infarction (nstemi) between a group of patients with type 2 diabetes mellitus and a nondiabetic group of patien...

Chronic hepatitis B (CHB) is a chronic inflammatory viral disorder. Several studies have suggested that the interval from the peak to the end of the electrocardiographic T wave (Tp-e) may correspond to the transmural dispersion of repolarisation and that increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. Impaired autonomic function has been describe...

Introduction: The ischemically injured myocardium contains a mixture of viable and non-viable tissue post-myocardial infarction (MI); thus, a method to discern the various zones would be of great value in clinical management. The traditional approach in treatment attempts to salvage the viable peri-infarcted areas, by pharmaceutical intervention. A popular route of treatment is providing Angiot...

BACKGROUND AND OBJECTIVES The study aimed to evaluate the correlation between electrocardiographic (ECG) parameters and presence and extent of coronary artery disease (CAD) to indicate the usefulness of these parameters as predictors of severity in patients with stable CAD. SUBJECTS AND METHODS Two hundred fifty patients, without a history of any cardiovascular event were included in the stud...

BACKGROUND Inflammatory markers are increased during vaso-occlusive crisis (VOC) in adult patients with sickle cell anemia (SCA), but this is not clear in clinical steady state. AIM The present study aims to establish the frequency and intensity of bone pain episodes in adult patients with SCA in clinical steady state and to determine the correlation between different inflammatory markers, ot...

Objectives: To examine whether the favourable effects on endothelial function, vascular angiotensin converting enzyme (ACE) activity, cardiac remodelling, autonomic function, and QT intervals of spironolactone in combination with ACE inhibitor also occur in patients with New York Heart Association class I–II congestive heart failure (CHF) taking optimal treatment (including b blockers). Methods...

A method for reliable quantification of Pneumocystis carinii in research models of P. carinii pneumonia (PCP) that is more convenient and reproducible than microscopic enumeration of organisms would greatly facilitate investigations of this organism. We developed a rapid quantitative touchdown (QTD) PCR assay for detecting P. carinii f. sp. carinii, the subspecies of P. carinii commonly used in...