The 4-anilinoquinazoline (4-AQ) derivative gefitinib (Iressa) is an oral epidermal growth factor receptor tyrosine kinase inhibitor. Oral administration of 4-AQ molecules, such as gefitinib, inhibits ATP-binding cassette (ABC) transporter-mediated drug efflux and strongly increases the apparent bioavailability of coadministered drug molecules that are transporter substrates. Based on in vitro s...

The Extreme Male Brain (EMB) theory posits that autistic traits are linked to excessive exposure to testosterone in utero. While findings from a number of studies are consistent with this theory, other studies have produced contradictory results. For example, some findings suggest that rather than being linked to hypermasculinization for males, or defeminization for females, elevated levels of ...

(1.1) f(aq + b) = f(aq) + f(b) or f(aq + b) = f(aq)f(b) for all r ≥ 0, a ≥ 0 and 0 ≤ b < q. Note that these equations force f(0) = 0 or f(0) = 1 respectively. These functions are called q-additive and q-multiplicative, respectively. It is easy to see that the functional equations imply that these functions are defined for all integers, when the values f(aq) are known for 1 ≤ a ≤ q − 1 and all r...

Let V ∼= Fq be a v-dimensional vector space over the finite field Fq with q elements. By [ V k ] we denote the set of all k-dimensional subspaces in V . Its size is given by the q-binomial coefficient [ v k ]q = ∏k−1 i=0 qv−qi qk−qi for 0 ≤ k ≤ v and 0 otherwise. The set of all subspaces of V forms a metric space associated with the so-called subspace distance dS(U,W ) = dim(U + W ) − dim(U ∩ W...

background: animal bites considered as one of the issues and problems of public health that potentially has the risk of rabies disease. this study was conducted to determine the epidemiology of animal bite in aq qala city during the years1998-2009. methods: in this descriptive cross-sectional study, 13142 cases of animal bite recorded in aq qala city rabies treatment center selected by census m...

Introduction: Rabies is one of the most important infectious diseases and animal bites are increasing in Iran. Due to the significance of the subject, the current study was designed and conducted with the aim of determining Animal bite status and its contributors in Aq-Qala district, Golestan province, Iran. Materials and methods: This is a data-based study with descriptive approach carrie...

Adversity Quotient (AQ) is one of the probable indicators a person’s success in life. It useful to predict attitude, mental stress, perseverance, longevity, learning, and response changes environment. An AQ measures ability person deal with adversities his or her This study assess level adolescents Lucknow city. The was conducted among 150 (10–19 years), out which 79 were boys 71 girls. Respons...

The hydroxide anion plays an essential role in many chemical and biochemical reactions. But a molecular-scale description of its hydration state, and hence also its transport, in water is currently controversial. The statistical mechanical quasichemical theory of solutions suggests that HO.[H2O]3(-) is the predominant species in the aqueous phase under standard conditions. This result agrees wi...