نتایج جستجو برای: q12
تعداد نتایج: 725 فیلتر نتایج به سال:
The majority of acute promyelocytic leukemia (APL) cases are characterized by the presence of a promyelocytic leukemia–retinoic acid receptor alpha(RARA) fusion gene. In a small subset, RARA is fused to a different partner, usually involved in regulating cell growth and differentiation. Here, we identified a novel RARA fusion transcript, BCOR-RARA, in a t(X;17)(p11;q12) variant of APL with uniq...
Creation of fusion genes by balanced chromosomal translocations is one of the hallmarks of acute myeloid leukemia (AML) and is considered one of the key leukemogenic events in this disease. In t(12;13)(p13;q12) AML, ectopic expression of the homeobox gene CDX2 was detected in addition to expression of the ETV6-CDX2 fusion gene, generated by the chromosomal translocation. Here we show in a murin...
5. Gangat N, Strand J, Lasho TL, et al. Cytogenetic studies at diagnosis in polycythemia vera: clinical and JAK2V617F allele burden correlates. Eur J Haematol 2008;80:197-200. 6. Diez-Martin JL, Graham DL, Petitt RM, Dewald GW. Chromosome studies in 104 patients with polycythemia vera. Mayo Clin Proc 1991;66:287-99. 7. Rowley JD. Abnormalities of chromosome 1 in myeloproliferative disorders. Ca...
We report an unusual case of a 55 year old Japanese woman with a seminoma but relatively normal menses. The patient was a phenotypic female with late onset menarche (18 years of age), who was amenorrhoeic for the first year, followed by menses of one to three days' slight flow with dysmenorrhoea, but an otherwise normal menstrual history. A typical seminoma was removed from the left adnexal reg...
The current study involves the fabrication of oral bioadhesive bilayer matrices of narrow absorption window drug baclofen and the optimisation of their in vitro drug release and characterisation. Statistical design of experiments, a computer-aided optimisation technique, was used to identify critical factors, their interactions and ideal process conditions that accomplish the targeted response(...
abstract regarding the imprecise or fuzzy data on the agriculture activities, applying models based on fuzzy data may be useful. in line with this condition this study tries to compare the ability of possiblistic programming approach in developing optimal solution with fuzzy and deterministic programming. to get this objective a data set obtained from 90 farmers of kohgilooye region, gathered i...
Factor market failures can limit adoption of profitable technologies. We leverage a plot-level spatial regression discontinuity design in the context irrigation use by farmers provided free access to water. Using boosts profits 43–62 percent. Yet, only irrigate 30 percent plots because labor costs. demonstrate inefficient use, showing irrigating one plot reduce their on other plots. This ineffi...
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