na2so4 as an inexpensive and effective catalyst has provided a green protocol for the synthesis of tetrahydrobenzo[b]pyran, pyrano[2,3-d]pyrimidinone and dihydropyrano[3,2c]chromene derivatives from the three-component domino reaction of aromatic aldehydes and malononitrile with 4-hydroxycoumarin/ dimedone/ barbituric acid in ethanol/water as a mixture of solvent that, this mixture entirely is ...

Chemotherapy represents the most applied approach to cancer treatment. Owing frequent onset of chemoresistance and tumor relapses, there is an urgent need discover novel more effective anticancer drugs. In search for therapeutic alternatives treat disease, a series hybrid pyrazolo[3,4-d]pyrimidin-4(5H)-ones tethered with hydrazide-hydrazones, 5a–h, was synthesized from condensation reaction pyr...

Hexagonal mesoporous silica (SBA-15) was prepared and then functionalized by(3-mercaptopropyl)trimethoxysilane. The obtained 3-mercaptopropyl functionalized SBA-15 (SBA-Pr-SH) was then oxidized using H2O2 in methanol under an acidic condition to give sulfonic acid functionalized mesoporous silica (SBA-Pr-SO3H). Th...

Soft robots are susceptible to premature failure from physical damages incurred within dynamic environments. To address this, we report an elastomer with high toughness, room temperature self-healing, and strong adhesiveness, allowing both prevention of recovery for soft robotics. By functionalizing polyurethane hierarchical hydrogen bonds ureido-4[1H]-pyrimidinone (UPy) carboxyl groups, toughn...