Animals with hippocampal lesions, induced by aspiration, are inferior to cortical control and normal animals in providing some aspects of maternal care needed for the proper survival of their young. Pup survival of animals with hippocampal lesions is significantly lower than pup survival of cortical control and normal animals. Nest construction of dams with hippocampal lesions is inferior to th...

Objectives: The study was aimed to evaluate the roles of Lactobacillus acidophilus supplementation in maintaining intestinal epithelial integrities, tight junction proteins, and adhesion molecules non-specific diarrhea.
 Methods: In this study, we used pre-weaned BL/6 pups (3 weeks age, same litters) as a model animal. We supplied non-sterilized poor-quality water experimental (n=7) develo...

Obesity is a serious and concerning disease for public health. Breastfeeding crucial formetabolic programming plays an important role in controlling newborn metabolism. Theaim of this study was to analyze weight gain milk consumption male femalenewborn rats whose mothers were fed high-calorie diet during the breastfeeding period. Atdelivery, female Wistar divided into two groups, one hypercalor...

BACKGROUND AND PURPOSE Germinal matrix hemorrhage-intraventricular hemorrhage is the most common neurological problem of premature infants. Despite this, mechanisms of brain injury from intraventricular hemorrhage are elusive. We hypothesized that germinal matrix hemorrhage-intraventricular hemorrhage, by induction of NAD(P)H oxidases, might cause oxidative/nitrosative stress contributing to br...

Neonatal maternal separation (MS) predisposes adult rats to develop stress-induced mucosal barrier dysfunction/visceral hypersensitivity and rat pups to develop colonic epithelial dysfunction. Our aim was to examine if enhanced epithelial permeability in such pups resulted from abnormal regulation by enteric nerves. Pups were separated from the dam for 3 h/day (days 4-20); nonseparated (NS) pup...

1. The effects of starvation and refeeding on the disposal of oral [14C]triolein between 14CO2 production and 14C-lipid accumulation in tissues of virgin rats, lactating rats and lactating rats with pups removed were studied. 2. Starvation (24 h) increased 14CO2 production in lactating rats and lactating rats with pups removed to values found in virgin rats. This increase was accompanied by dec...

BACKGROUND RFamide-related peptide-3 (RFRP-3) inhibits gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in rats. This study evaluates the effects of litter size and suckling intensity on RFRP mRNA expression in the dorsomedial hypothalamic nucleus (DMH) of rats. MATERIALS AND METHODS A total of 32 pregnant and 4 non-lactating ovariectomized (control group) Sprague-...

Children of depressed parents exhibit high rates of emotion-dysregulation, characterized by excessive withdrawal or approach strategies toward the mother in infancy. The understanding of factors affecting the establishment of these behavioral deficits is limited. The current study utilized two genetic animal models of depression, the Wistar-Kyoto (WKY) and Flinders Sensitive Line (FSL) rat stra...

1. Rat pups developed chronic protein insufficiency resulting from malnutrition diet in utero while their dams received 40 g protein/kg diet. 2. Before weaning they were found to have decreased salivary amylase (EC 3.2.1.1) and aminopeptidase activities. 3. A complete diet (250 g protein/kg) rapidly restored salivary amylase activity before weight normalization. However, renourished pups (malno...