BACKGROUND Hemodynamic assistance with a miniature intracardiac pump may fill the treatment gap between use of an intraaortic balloon pump (IABP) and the current, more invasive ventricular assist devices. The objective of this study was to compare the hemodynamic efficacy of a miniature intracardiac pump device with that of IABP. METHODS AND RESULTS Reversible acute mitral regurgitation (AMR)...

Clinically adequate implementation of physiological control of a rotary left ventricular assist device requires a sophisticated technique such as the recently proposed method based on the Frank-Starling mechanism. In this mechanism, the stroke volume of the heart increases in response to an increase in the volume of blood filling the left ventricle at the end of diastole. To emulate this proces...

To compare the efficiency of pulmonary artery balloon counterpulsation and a centrifugal flow pump in reversing the hemodynamic consequences of acute right-sided heart failure, we employed both devices in 14 Yorkshire pigs in which right ventricular infarction was created via surgical ligation of branches of the right coronary artery. Pulmonary artery balloon counterpulsation improved some of t...

OBJECTIVES To develop a multivariate predictive risk score of perioperative in-hospital stroke after coronary artery bypass grafting (CABG) surgery. METHOD A total of 26 347 patients were enrolled from 21 Spanish hospital databases. Logistic regression analysis was used to predict the risk of perioperative stroke (ictus or transient ischaemic attack). The predictive scale was developed from a...

BACKGROUND Pump thrombosis in durable continuous-flow pumps is a barrier to long-term mechanical circulatory support. Earlier Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) data identified an increasing risk of pump thrombosis in recent years with the HeartMate II (HMII) left ventricular assist device. The current analysis examines pump thrombosis in the patient ...

introduction: heart failure is a major hazard for public health. despite recent advance in medical therapy, there is not enough information on the outcome of off-pump coronary artery bypass (opcab) and medical therapy on the patients with severe ventricular dysfunction and triple-vessel (cad). this study aimed to compare treatment outcomes and mortality rate in patients undergoing off-pump coro...


 CADTH recommends that Jardiance should be reimbursed for the treatment of chronic heart failure as an adjunct to standard-of-care therapy if certain conditions are met.
 only covered treat patients 18 years and older whose is unable pump enough blood keep up with body’s needs (heart failure) because either too weak reduced ejection fraction [HFrEF]) or stiff preserved [HFpEF]). The ...

Shao, Qiming, Bin Ren, Harjot K. Saini, Thomas Netticadan, Nobuakira Takeda, and Naranjan S. Dhalla. Sarcoplasmic reticulum Ca transport and gene expression in congestive heart failure are modified by imidapril treatment. Am J Physiol Heart Circ Physiol 288: H1674–H1682, 2005. First published December 2, 2004; doi: 10.1152/ajpheart.00945.2004.—This study was designed to test the hypothesis that...