BACKGROUND Pulsed dye laser (PDL) is the gold standard for treatment of port-wine stain (PWS) birthmarks but multiple treatments are required and complete resolution is often not achieved. Posttreatment vessel recurrence is thought to be a factor that limits efficacy of PDL treatment of PWS. Imiquimod 5% cream is an immunomodulator with antiangiogenic effects. OBJECTIVE We sought to determine...

BACKGROUND Facial soft tissue injury can be one of the most challenging cases presenting to the plastic surgeon. The life quality and self-esteem of the patients with facial injury may be compromised temporarily or permanently. Immediate reconstruction of most defects leads to better restoration of form and function as well as early rehabilitation. OBJECTIVES The aim of this study was to pres...

Editor Angiokeratomas are rare vascular lesions with secondary verrucous epidermal changes. The exact pathogenesis is unknown, although genetic factors, pregnancy, chilblains, trauma and tissue asphyxia are known causal factors. We report for the first time on the successful treatment of ‘solitary and multiple papular’ type angiokeratomas of the lower extremities with a synchronized dual wavele...

Atmospheric NO was detected in a long-path absorption experiment using a frequency-doubled dye laser, twice Raman shifted in H(2) to 227 nm. Apart from measurements employing a distant retroreflector, the potential of range-resolved lidar measurements was investigated.

Illumination systems with tunable spectrums have been receiving an increasing amount of attention due to their wide application and unique capability. This paper proposes a programmable light source in the visible range based on the combination of a prism and an echelle grating. A supercontinuum laser is utilized as the primary source, whose echellogram is projected to a digital mirror device f...

The passive mode locking of a cw Coumarin 6 dye laser in a colliding-pulse ring configuration is reported. Pulses of less than 500-fsec duration have been obtained from 518 to 554 nm, with the shortest pulses obtained being of 96-fsec duration.

BACKGROUND AND OBJECTIVE The objective of this study was to improve port wine stain (PWS) therapeutic outcome in response to laser therapy. Our specific aim was to determine whether the combined use of pulsed dye laser (PDL) therapy and topical Imiquimod versus PDL alone can improve PWS therapeutic outcome. STUDY DESIGN/MATERIALS AND METHODS This pilot study involved a retrospective review of...

Organic solid-state lasers (OSSLs) with distributed feedback structures can detect nanoscale materials and therefore offer an attractive sensing platform for biological and medical applications. Here we investigate the lasing characteristics, i.e., the threshold and slope efficiency, as a function of the grating depth in OSSL devices with distributed feedback (DFB) structure fabricated using ph...

BACKGROUND Pulsed dye laser (PDL) is a commonly utilized treatment for port wine stain birthmarks (PWS) in the United States; however, results are variable and few patients achieve complete removal. Photodynamic therapy (PDT) is commonly used in China, but treatment associated photosensitivity lasts several weeks and scarring may occur. We propose an alternative treatment option, combined PDT+P...

Restoration of form and function after burn injury remains challenging, but emerging laser and pulsed light technologies now offer hope for patients with hypertrophic scars, which may be associated with persistent hyperemia, chronic folliculitis, intense pruritis, and neuropathic pain. In addition to impairing body image, these scars may limit functional recovery, compromise activities of daily...