We present an approach to measure pulsatile total retinal arterial blood flow in humans and rats using ultrahigh speed Doppler OCT. The axial blood velocity is measured in an en face plane by raster scanning and the flow is calculated by integrating over the vessel area, without the need to measure the Doppler angle. By measuring flow at the central retinal artery, the scan area can be very sma...

background: aneurysm is a blood-filled bulge in the wall of vessels that occurred in abdominal aortic and cerebral vessels. the dilation of artery leads to aneurysm. methods: three dimensional modelling was utilized for a patient with cerebral aneurysm and a normal subject, and additional fluid-structural interaction simulation was performed. we consider pulsatile blood velocity as inlet, and b...

the purpose of this research is to numerically investigate the interaction of pulsatile flow of blood with an axisymmetric artery in various percentages of stenosis. the carreau non-newtonian model and the generalized maxwell rheological model were used to model the blood fluid and the viscoelastic wall of arterial, respectively. the innovation of the present research is modeling of viscoelasti...

PURPOSE To determine the effect of intravenously administered histamine on both retinal and choroidal blood flow in humans. METHODS A randomized, double-masked, two-way crossover study was performed in 14 healthy volunteers. Placebo or histamine was administered intravenously in stepwise increasing doses (0.08 microg/kg/min, 0.16 microg/kg/min, and 0.32 microg/kg/min). Retinal vessel diameter...

In this paper, we study the blood flow in the real model of the right coronary artery -bypass graft system under the real pulsatile condition. The human blood is assumed as an incompressible Non-Newtonian fluid and its flow is modeled by the unsteady state Navier-Stokes equations and the continuity equation. The effect of the existence and intensity of a stenosis in the right coronary artery on...

Numerical flow simulation is useful for understanding fluid phenomena such as blood flow or pulse wave propagation in the systemic arteries. For numerical analysis of intravascular flow, it is important to consider not only incompressible assumption and blood viscosity but also the viscoelasticity of the blood vessel wall; however, blood flow in vivo is complicated because of the unsteadiness o...