Aim The aim of this study was to evaluate the cytotoxicity effects of experimental gypsum-based biomaterial prepared with various concentrations of chitosan (Gyp-CHT). Materials and Methods The study was performed using cell viability assay for mitochondrial dehydrogenase activity in stem cells from human exfoliated deciduous teeth (SHED), after 1, 2, and 3 days of exposure to the biomaterial...

A comprehensive understanding of tooth development, etiology, and pathogenesis of pulp and periradicular tissues supports the underlying principles for endodontic treatment. Innovative therapies apply biological modulators that have been identified during tooth and bone embryogenesis and later became cloned for experimental and clinical application. These modulators are intended to improve trea...

Two hundred direct pulp capping procedures were conducted in the present study. One hundred of them were performed with the CO2 laser, and 100 were conducted conventionally as a control by using a calcium hydroxide preparation. Follow-up examinations were performed after 1 wk and monthly for 12 months after treatment. Thermal tests were used for vitality assessments and laser Doppler flowmetry ...