Effects of raloxifene have been documented in the systemic circulation. However, its impact on the pulmonary circulation is unclear. The present study investigated the role of gender, endothelial modulation, and Ca(2+) channel in relaxations evoked by raloxifene in rat pulmonary arteries and veins. Vascular responses were studied on isolated pulmonary blood vessels mounted in a myograph and con...

Pulmonary veno-occlusive disease (PVOD) is an uncommon in humans and animals caused by pulmonary hypertension (PH). The aim of this study was to investigate pathomorphological findings PVOD a cat. A mass detected the right atrium with echocardiography 11-year-old male Following treatments, necropsy cat performed after death due respiratory failure. Macroscopically, masses were mesenteric lymph ...

A case is reported of recurrence of paroxysmal atrial fibrillation after pulmonary vein ablation. A second procedure achieved isolation of three pulmonary veins and showed persistence of pulmonary vein tachycardia in one with implications concerning the electrophysiology of atrial fibrillation.

Partial anomalous pulmonary venous connection is a rare congenital anomaly in which one or more pulmonary veins are connected to the venous circulation. The condition is frequently misdiagnosed, and usually identified by transesophageal echocardiography or invasive cardiac catheterization. We present the case of a 26-year-old female with new onset dyspnea on exertion who was diagnosed with the ...

OBJECTIVES To quantify and study the distribution of innervation of the left atrium and the pulmonary veins in humans. BACKGROUND Damage to cardiac nerves has been hypothesized as the explanation for successful radiofrequency ablation of atrial fibrillation. METHODS From January 2003 to September 2003, histologic and quantitative studies of innervation of the left atrium and the pulmonary v...

To cite: Morcos KHK, Roditi G, Craig S. Thorax Published Online First: [please include Day Month Year] doi:10.1136/thoraxjnl2012-202869 HISTORY A 30-year-old man with a 3 day history of increasing breathlessness and frank haemoptysis was suspected of having pulmonary embolism and anticoagulated with heparin. Haemoptysis worsened so anticoagulation was reversed and he was transferred to our inst...

The heart pumps oxygenated blood through the aorta to smaller arteries. After the blood supplies nutrients to vital organs, it returns through veins for reoxygenation in the lungs (Figures 1 and 2). Blood clots called deep vein thrombi (DVT) often develop in the deep leg veins. Pulmonary embolism (PE) occurs when clots break off from vein walls and travel through the heart to the pulmonary arte...

Early diagnosis and surgical correction is highly important for survival. In the evaluation of TAPVC, imaging methods have been used. Recent advances Total anomalous pulmonary venous connection (TAPVC) is a rare congenital cardiac anomaly in which the pulmonary veins fail to connect with the left atrium and connect directly to the right atrium or to one of the systemic veins. Early diagnosis an...

Patients with fibrosing mediastinitis causing obstruction of pulmonary veins and arteries may present with many of the historic, physical, and laboratory findings of patients with pulmonary hypertension due to chronic thrombotic obstruction of major pulmonary arteries. Because the latter is subject to surgical correction, and the former is not, it is important to differentiate between the two a...