This study aims to describe the haemodynamic and survival characteristics of patients with pulmonary hypertension in the recently individualised syndrome of combined pulmonary fibrosis and emphysema. A retrospective multicentre study was conducted in 40 patients (38 males; age 68+/-9 yrs; 39 smokers) with combined pulmonary fibrosis and emphysema, and pulmonary hypertension at right heart cathe...

STUDY OBJECTIVES Evidence exists that HIV-seropositive individuals may be at increased risk for the development of precocious pulmonary emphysema. HIV infection is also associated with antioxidant deficiency in both the serum and lungs, and it is therefore possible that increased oxidant stress may contribute to parenchymal lung injury occurring in the setting of HIV. We sought to determine the...

Combined pulmonary fibrosis and emphysema (CPFE) is a common yet under diagnosed entity with imaging findings of both pulmonary emphysema and fibrosis.Many have challenged the definition of CPFE and there still exists a lot ofcontroversy over various aspects of this syndrome. Initially considered to represent a chance coexistence of two separateentities, CPFE is now being increasingly recognize...

CONFLICT OF INTEREST NONE DECLARED. INTRODUCTION P-wave abnormalities on the resting electrocardiogram have been associated with cardiovascular or pulmonary disease. So far, "Gothic" P wave and verticalization of the frontal plane axis is related to lung disease, particularly obstructive lung disease. AIM We tested if inverted P wave in AVl as a lone criteria of P wave axis >70° could be sc...

Combined pulmonary fibrosis and emphysema is a condition occurring mainly in male smokers, presenting different lung mechanics and gas exchange abnormalities than emphysema or pulmonary fibrosis alone. We report the case of an elderly man, former heavy smoker, who presented with progressive exertional dyspnea for 1 year. Lung function tests showed near normal spirometry and lung volumes but mar...