PATIENT Female, 42. FINAL DIAGNOSIS Acute pulmonary embolism. SYMPTOMS Chest pain • dyspnea. MEDICATION Streptokinase • Warfarin. CLINICAL PROCEDURE .- SPECIALTY Cardiology and Neoplasm. OBJECTIVE Management of emergency care. BACKGROUND Deep venous thrombosis (DVT) and subsequent pulmonary embolism (PE) caused by pelvic vein compression are rare and life-threatening complications...

Pulmonary embolism is a common condition with a high mortality. We describe a previously healthy 68-year-old male who suffered three pulmonary embolisms during a short period of time, including two embolisms while on anticoagulant treatment. This paper illustrates three important points. (1) The importance of optimal anticoagulant treatment in the prevention of pulmonary embolism reoccurrence. ...

Multiple myeloma is considered a hypercoagulable state due to several mechanisms such as the increased IL-6 and immunoglobulins production, the defective fibrinolytic mechanism, and the acquired resistance to activated protein C that are involved in the pathogenesis and clinical futures of the disease. We describe a case of a female patient who presented to the hospital with pulmonary embolism ...

BACKGROUND Thrombolytic treatment has been shown to accelerate resolution of major pulmonary embolism and lead to a rapid improvement of right-side hemodynamics. However, the association between these favorable effects and the clinical outcome of patients who have no severe hemodynamic compromise at presentation remains unknown. METHODS AND RESULTS The present multicenter registry included 71...

Thrombotic disorders, such as myocardial infarction, ischemic stroke, peripheral arterial disease, deep venous thrombosis, pulmonary embolism, or other embolic diseases that are responsible for worldwide mortality and morbidity, are manifestations of the formed thrombi by blood clots during a pathologic blood coagulation process. Once thrombi are formed, the only way to resolve the blood clot i...

This is a case report of massive pulmonary embolism, an uncommon condition in the paediatric population, in a boy who presented with acute onset shortness of breath. The use of tissue plasminogen activator, a form of thrombolytic therapy not commonly used in children, reversed the critical condition of our patient who eventually made a good recovery. Literature review of the disease was perform...

The new generation of non-vitamin K antagonist oral anticoagulants (NOACs) have been welcomed as a convenient alternative to warfarin. Three new oral anticoagulants, dabigatran etexilate, rivaroxaban and apixaban have been approved for the prevention of stroke and systemic embolism (SSE) in patients with atrial fibrillation (AF) and the prevention of venous thromboembolic events (VTEs) in patie...

The principal clinical syndromes that result are acute ST elevation myocardial infarction (STEMI), deep vein thrombosis, pulmonary embolism, acute ischemic stroke, acute peripheral arterial occlusion, and occlusion of indwelling catheters. Of these, AMI accounts for maximum number of morbidity and mortality. Over the last century, thrombolytic therapy has gained prominence in the management of ...

Direct-acting oral anticoagulants include dabigatran, which is a thrombin inhibitor, and rivaroxaban, apixaban, edoxaban, are anti-Xa agents. These administered in the secondary prophylaxis treatment of venous thromboembolism (VTE) pulmonary embolism (PE), VTE that may develop after major elective orthopedic surgery, reducing stroke systemic occur non-valvular atrial fibrillation, whereas its u...