(Cell 143, 456–469; October 7, 2010) This paper introduced a new methodology, BLINC, for detecting the trans-synaptic binding of neurexin and neuroligin proteins, and applied BLINC to study the interaction dynamics of these proteins in neurons. Since this publication, my laboratory has found that BLINC cannot be reproduced in neurons using the constructs and protocols described in this paper. A...

www.thelancet.com Published online August 22, 2017 http://dx.doi.org/10.1016/S0140-6736(17)31365-X 1 Submissions should be made via our electronic submission system at http://ees.elsevier.com/ thelancet/ Oxford University, without consulting our group, the very investigators involved in the WHO study. When we learned that WHO and Oxford University were about to settle the case without having ad...

OBJECTIVES Despite the fact that research fraud and misconduct are under scrutiny in the field of orthopaedic research, little systematic work has been done to uncover and characterise the underlying reasons for academic retractions in this field. The purpose of this study was to determine the rate of retractions and identify the reasons for retracted publications in the orthopaedic literature....

1 Department of Pharmacology, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran; 2 Department of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran; 3 Student Research Committee, Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; 4 Toxicology and Diseases Group, Pharm...

991022.html 2. PHS policy on instruction in the responsible conduct of research (RCR). July 17, 2000. Available at: http://ori.dhhs.gov/TheRCRPolicy.htm 3. Code of Federal Regulations 50.102 4. Commission on Research Integrity. Integrity and misconduct in research. Washington, DC: US Department of Health and Human Services, 1995:13 5. Friedman PJ. Advice to individuals involved in misconduct ac...

In recent years, several high-profile cases related with misconduct by doctors and medical students have led to increased media interest and public concern regarding doctors who fail to maintain the expected professional standards. In response to these concerns and the increasing awareness of the social responsibility of medicine, the importance of professionalism in medical school is receiving...

Malpractice insurance premiums for physicians have increased at an average rate of over 30 percent per year. This rate is significantly higher than health care cost inflation and the increase in physician costs. Trends indicate that malpractice related costs, both liability insurance and defensive medicine costs, will continue to increase for the near future. Pressures to limit physician costs ...

Background Publication bias is a form of scientific misconduct. It threatens the validity of research results and the credibility of science. Although several tests on publication bias exist, no in-depth evaluations are available that examine which test performs best for different research settings. Methods Four tests on publication bias, Egger's test (FAT), p-uniform, the test of excess sign...

All Atomic Weapons Employer employees who worked in any building at the Wah Chang facility in Albany, Oregon, for the operational period from January 1, 1971 through December 31, 1972, for a number of work days aggregating at least 250 work days, occurring either solely under this employment or in combination with work days within the parameters established for one or more other classes of empl...

The frequency with which scientists fabricate and falsify data, or commit other forms of scientific misconduct is a matter of controversy. Many surveys have asked scientists directly whether they have committed or know of a colleague who committed research misconduct, but their results appeared difficult to compare and synthesize. This is the first meta-analysis of these surveys. To standardize...