In this issue of Circulation, Detre et all review the incidence and outcome of periprocedural coronary artery occlusion following percutaneous transluminal coronary angioplasty (PTCA) in the second phase of the National Heart, Lung, and Blood Institute's (NHLBI) PTCA Registry. This registry examined the results in 1,801 patients managed during 1985-1986 with an initial PTCA not in the setting o...

BACKGROUND AND PURPOSE Previous studies have reported encouraging results with percutaneous transluminal coronary angioplasty (PTCA) in patients with acute myocardial infarction (AMI) and cardiogenic shock (CS). However, PTCA fails in many patients and the mortality rate associated with the procedure is very high. This study sought to assess the determinants of successful coronary artery bypass...

Background—In the era of primary percutaneous transluminal coronary angioplasty (PTCA), it is important to judge whether myocardium within acute ischemic injury is viable. This study sought to investigate parameters derived from the coronary blood flow velocity spectrum immediately after primary PTCA in patients with acute myocardial infarction and to elucidate the clinical value of coronary bl...

OBJECTIVE The goal of this study was to determine whether the haptoglobin (Hp) genotype was predictive of restenosis and major adverse cardiac events (MACEs) after percutaneous transluminal coronary angioplasty (PTCA) in individuals with diabetes. RESEARCH DESIGN AND METHODS A consecutive series of 935 diabetic patients treated with oral agents and/or insulin were followed for 1 year after PT...

BACKGROUND In PTCA patients with multivessel coronary artery disease, incomplete revascularization (IR) is the result of both pre-PTCA strategy and initial lesion outcome. The unique contribution of these components on long-term patient outcome is uncertain. METHODS AND RESULTS From the Bypass Angioplasty Revascularization Investigation (BARI), 2047 patients who underwent first-time PTCA were...

Early restenosis is the major complication of percutaneous transluminal coronary angioplasty (PTCA), occurring in approximately 30% of all initially successful procedures. The D/I polymorphism of the ACE gene, which has variably been reported to represent a risk factor for manifestations of ischemic heart disease, has recently been implicated in the pathophysiology of restenosis after PTCA by s...

Regional coronary blood flow and myocardial metabolism were evaluated in a patient who underwent percutaneous transluminal coronary angioplasty (PTCA). Angioplasty increased coronary luminal diameter and reduced trans-stenotic gradient. Before PTCA, angina pectoris developed during sustained rapid atrial pacing and was associated with abnormal lactate metabolism and a mild increase in coronary ...

Background Trapidil is an antiplatelet drug with specific platelet-derived growth factor antagonism and antiproliferative effects in the rat and rabbit models after balloon angioplasty. Methods and Results The Studio Trapidil versus Aspirin nella Restenosi Coronarica (STARC) is a multicentric, randomized, double-blind trial to assess the effects of trapidil in angiographic restenosis prevention...

To the Editor: Grines et al1 once more reiterate their enthusiasm for primary percutaneous transluminal coronary angioplasty (PTCA) in STsegment elevation myocardial infarction. We agree that this maneuver is extremely attractive for most cardiologists, yet we believe that data should be examined for what they actually show. The Keeley et al2 review shows only a trend in mortality reduction whe...

background: angioplasty is one of the most common methods for treating coronary artery diseases. however, a large number of those undergoing this treatment face psychological problems that negatively affect the quality of their life and recovery. we aimed to determine the effects of discharge planning on stress, anxiety, and depression in patients undergone percutaneous transluminal coronary an...