background: immune reactions have been reported to be involved in the destruction of retinal ganglion cells (rgcs) in glaucoma. objective: to investigate the role of major histocompatibility complex class i-related chain a and b (mica and micb) molecules in the pathogenesis of glaucoma. methods: aqueous humor and serum samples from 15 glaucoma patients and 45 patients with cataract, undergoing ...

In this perspective, we discuss the use of an anti-fibrotic agent Decorin to treat established fibrosis associated with glaucoma originally published by Hill et al. (2015). Glaucoma describes a group of progressive optic neuropathies that have the potential to cause irreversible blindness, for which it is recognized that a main risk factor is raised intraocular pressure (IOP). Currently, there ...

PURPOSE To determine the distribution of mRNA expression of the trabecular meshwork-induced glucocorticoid response protein/myocilin (TIGR/MYOC) in human trabecular meshwork. METHODS In situ hybridization using a 1.25-kb probe obtained from reverse transcription-polymerase chain reaction of TIGR/MYOC cDNA was performed to determine the location of cell labeling within the different regions of...

purpose: to determine the incidence and risk factors associated with glaucoma following congenital cataract surgery (ccs) in children under age of 15 methods: this prospective cohort (since 2006) consisted of children less than 15 years of age who underwent cataract surgery with or without intraocular lens (iol) implantation. the role of the following factors on the development of glaucoma afte...

introduction: glaucoma is one of the leading causes of blindness throughout the world. some studies have suggested a relationship between glaucoma and sensorineural hearing loss, while others have found no evidence of an association. we performed a study to determine whether there is a significant difference in hearing of patients with glaucoma and a match control population. methods: in this c...

glaucoma is a major cause of blindness worldwide. a single nucleotide polymorphism of the mthfr gene (c677t) has been associated with susceptibility to this disease, although this is controversial in the last decade. in this study, the possible association between the mthfr c677t polymorphism and the risk of developing primary open angle (poag) and pseudoexfoliation glaucoma (pexg) was investig...

OBJECTIVE The aim of this study was to evaluate the demographic characteristics and intraoperative complications of cataract surgery in patients with pseudoexfoliation syndrome (PEX). MATERIALS AND METHODS Cases of 225 eyes (80 eyes with pseudoexfoliation and 145 eyes without pseudoexfoliation as the control group) that underwent phacoemulsification cataract surgery and IOL implantation at th...

purpose : to evaluate the efficacy and safety of pars plana ahmed valve implant combined with pars plana vitrectomy and endolaser photocoagulation for the treatment of neovascular glaucoma in patients with vitreous hemorrhage. methods : retrospectively, we evaluated the records of 18 eyes of 17 consecutive neovascular glaucoma patients who had undergone pars plana vitrectomy and pars plana ahme...

Objetivo: Analisar as características do Glaucoma. Revisão bibliográfica: O glaucoma é um grupo de doenças cuja característica comum a degeneração progressiva nervo óptico, com perda células ganglionares da retina, afinamento camada fibras nervosas retina e aumento escavação disco óptico. Os sintomas visuais costumam ser uma tardia glaucoma, quando doença já está muito avançada. Dentre os muito...