نتایج جستجو برای: proviral load
تعداد نتایج: 150243 فیلتر نتایج به سال:
The risk of disease associated with persistent virus infections such as HIV-I, hepatitis B and C, and human T-lymphotropic virus-I (HTLV-I) is strongly determined by the virus load. However, it is not known whether a persistent class I HLA-restricted antiviral cytotoxic T lymphocyte (CTL) response reduces viral load and is therefore beneficial or causes tissue damage and contributes to disease ...
A high frequency of proviral acquisition has previously been reported in the offspring of SWR/J-RF/J hybrid mice. In the present study, it was investigated whether this proviral acquisition would be useful for large-scale insertional mutagenesis studies. A population of SWR/J-RF/J hybrid mice with a predominantly SWR/J background was created. Lines of mice with such a background and partially c...
Koala retrovirus (KoRV) infection, endogenous in all northern koalas (Phascolarctos cinereus), has been found to occur at lower, but increasing, prevalence the Kangaroo Island and Mount Lofty Ranges koala populations South Australia. Proviral viral loads are also lower than Queensland koalas, which may be due exogenous spread of or related variable presence genes fragmented expression that posi...
Slow transforming retroviruses, such as the Moloney murine leukemia virus (M-MuLV), induce tumors upon infection of a host after a relatively long latency period. The underlying mechanism leading to cell transformation is the activation of proto-oncogenes or inactivation of tumor suppressor genes as a consequence of proviral insertions into the host genome. Cells carrying proviral insertions th...
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