A common strategy to identify new antiparasitic agents is the targeting of proteases, due their essential contributions parasite growth and development. Metacaspases (MCAs) are cysteine proteases present in fungi, protozoa, plants.

A complete analysis of the macroand microzooplankton of a warm monomictic lake indicates that Protozoa dominate the community numerically. During winter mixis, ciliates are found at densities of 1-8x 103.1iter-' and constitute up to 32% of the zooplankton community biomass. With summer stratification crustaceans decline, while both the relative and absolute abundance of protozoans and rotifers ...