in current study, a few sheep cystic livers and lungs were obtained from mashhad slaughter house and protoscolex were separated aseptically. thirty 6-week-old swiss mice were divided into 5 groups and two thousands of live protoscolices were inoculated intrapritoaneally in each mouse. in group 1 and 2 (prophylactic groups), mice were given 150 mg/kg of oral albendazole and mebendazole for 10 da...

we conducted this study to determine the level of immunity after vaccination of lambs with whole bodyechinococcus granulosus. to do so, 200 mature e. granulosus parasites, which were kept in 10% formalinefor 8 months, were obtained from the department of parasitology, school of veterinary medicine, ferdowsiuniversity of mashhad. the soluble protein of the parasite was prepared. the sample was h...

First step in developing an epitope-based vaccine is to predict peptide binding to the major histocompatibility complex (MHC) molecules. We performed computational analysis of unique available EgA31 sequence to locate appropriate antigenic propensity positions. T-cell epitopes with best binding affinity values of < 50% inhibitory concentration were selected using different available servers (Pr...

Diagnosis of hydatid disease (HD) is usually based on its clinical and radiologic presentation. However, radiologic appearances of bone lesions are nonspecific and mimic inflammatory diseases and neoplasms.6 Despite limited experience with fine needle aspiration biopsy (FNAB) in the evaluation of cystic bone lesions, HD is diagnosed in cytology.1-5 A 33-year-old woman presented with right hip p...

Objective(s): There are several scolicidal agents for inactivation of hydatid cyst protoscolices during surgery, but most of them are associated with adverse side effects such as sclerosing cholangitis and liver necrosis. The present study was aimed to evaluate scolicidal effects of various extracts of Nigella sativa seeds againstprotoscoleces of hydatid cyst in an in vitro model. Materials and...

Hydatid disease also known as echinococcosis is an endemic zoonotic infestation in cattle-raising regions of the world formed by the larval forms of cestodes belonging to the genus Echinococcus. This disease is mainly caused by the larval form of Echinococcus granulosus and Echinococcus alveolaris. Although hydatidosis is most often occurred in the liver [60%-70%] and lung [20%-30%], it can occ...