نتایج جستجو برای: protoporphyrin ix
تعداد نتایج: 20130 فیلتر نتایج به سال:
Cytochrome P-450 (CYP) 3A2 and CYP2C11 are sources of 70 and 30%, respectively, of N-vinylprotoporphyrin IX (N-vinylPP) formation after administration of 3-[(arylthio)ethyl]sydnone (TTMS) to rats. Female rats receiving TTMS were pretreated with dexamethasone, which induces CYP3A1 preferentially to CYP3A2. The resulting 12-fold increase in N-vinylPP formation showed that CYP3A1 was also a source...
The transport and intracellular trafficking of heme biosynthesis intermediates are crucial for hemoglobin production, which is a critical process in developing red cells. Here, we profiled gene expression in terminally differentiating murine fetal liver-derived erythroid cells to identify regulators of heme metabolism. We determined that TMEM14C, an inner mitochondrial membrane protein that is ...
Ferrochelatase from rat liver mitochondria was purified 628-fold with a 25% yield to apparent homogeneity. The purification procedure involved solubilization of the enzyme with sodium cholate, followed by ammonium sulfate fractionation and blue Sepharose CL-GB column chromatography. The molecular weight of the enzyme was estimated to be 42,000 by polyacrylamide gel electrophoresis in the presen...
Salt injury, as an abiotic stress factor, seriously affects the quality and yield of crops. This study was conducted by analyzing alternative splicing in control (CK), δ-aminolevulinic acid (ALA), NaCl, ALA + NaCl treatments wild jujube (Zizyphus spinosus (Bunge)Hu) using RNA-seq. It found that unique differential is closely related to alleviation salt analyzed intermediates chlorophyll synthes...
Photodynamic therapy (PDT) is based on photosensitizers activated by light of appropriate wavelength. Their activation leads to generation of singlet oxygen and free radicals responsible for the cytotoxic effect. The aim of this project was to compare the bactericidal effect of PDT using different porphyrin photosensitizers against a methicillin-resistant Staphylococcus aureus strain. Exogenous...
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