نتایج جستجو برای: prostaglandin e2
تعداد نتایج: 42460 فیلتر نتایج به سال:
BACKGROUND Recent studies have reported elevated prostaglandin levels in patients with renal artery stenosis and hypertension. To investigate whether a distinction between essential hypertension and hypertension with renal artery stenosis is possible by measuring eicosanoid excretion, we studied the excretion of these compounds in patients with essential hypertension and in hypertensives with c...
A case of uterine rupture following extra-amniotic prostaglandin E2 with a subsequent obstetrical complication is reported.
Response to Prostaglandin E2 Mediates Connecting Tubule Glomerular Feedback We thank Elijovich and Laffer1 for their interest in our article. First, we clarify that prostaglandin E2 is not the only mediator of connecting tubule glomerular feedback (CTGF). We had previously reported that about half of the CTGF response is mediated by epoxyeicosatrienoic acids, with the other half attributable to...
Prostaglandin E(2) (PGE(2)) plays a crucial role in the apparent link between tumor growth and chronic inflammation. Cyclooxygenase (COX)-2 and microsomal PGE(2) synthase-1, which are overexpressed in many cancers, are functionally coupled and thus produce massive PGE(2) in various tumors. Curcumin, a polyphenolic beta-diketone from tumeric with anti-carcinogenic and anti-inflammatory activitie...
The anti-inflammatory drug licofelone [=ML3000; 2-[6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl] acetic acid], currently undergoing phase III trials for osteoarthritis, inhibits the prostaglandin (PG) and leukotriene biosynthetic pathway. Licofelone was reported to suppress the formation of PGE(2) in various cell-based test systems, but the underlying molecular mechan...
BACKGROUND Induction of labour is a common obstetric procedure. Both mechanical (eg, Foley catheters) and pharmacological methods (eg, prostaglandins) are used for induction of labour in women with an unfavourable cervix. We aimed to compare the effectiveness and safety of induction of labour with a Foley catheter with induction with vaginal prostaglandin E2 gel. METHODS We did an open-label,...
Hyperproduced prostaglandin E2 by cyclooxygenase-2 and microsomal prostaglandin E synthase-1 evokes several pathophysiological responses such as inflammation and carcinogenesis. Our recent study demonstrated that Dioscorea japonica extract suppressed the expression of cyclooxygenase-2 and microsomal prostaglandin E synthase-1 and induced apoptosis in lung carcinoma A549 cells. In the present st...
Unilateral ureteral obstruction of rabbit kidney results, after 3 days, in an exaggerated release of prostaglandin E2 and thromboxane Az by the ex vivo perfused hydronephrotic kidney (HNK) but not by the surgically unaltered contralateral kidney (CLK). Both cyclooxygenase (PG endoperoxide synthetase) and thromboxane synthetase activities increased 20-40fold in cortical microsomes prepared from...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید