PURPOSE To provide patients and health care providers with calculated yearly costs of topical glaucoma medications. DESIGN Prospective, experimental, laboratory study. METHODS Using the average wholesale price and common dosing patterns, we calculated the theoretical yearly cost of glaucoma medications. RESULTS Calculated yearly cost ranged from $150.81 for generic timolol maleate 0.5% (F...

Platensimycin was recently discovered by Merck Research Laboratories and has created considerable interest given its potent antibacterial activity and mode of action. The use of RNA gene-silencing techniques and screening libraries of natural products allowed Merck to find this antibiotic which may have otherwise been missed using conventional methods. Interestingly, platensimycin has shown goo...

Vaccines that contain live attenuated varicella-zoster virus (VZV) (Varivax, ProQuad, and Zostavax [all products of Merck & Co., Inc.]) are contraindicated during pregnancy. To monitor the pregnancy outcomes of women inadvertently vaccinated with VZV-containing vaccines immediately before or during pregnancy, Merck and CDC established the Merck/CDC Pregnancy Registry for VZV-Containing Vaccines...

and the participants in the 2003 and 2004 Genesis of Clusters workshops for their comments on earlier drafts. We are grateful for research support from the Hewlett Foundation and the Merck Foundation.

Fixation was initiated by adding an equal volume of fixative solution, previously warmed to 37°C, to the cells after treatment with zinc oxide nanoparticles for 24 hours. The fixative solution contained 5% glutaraldehyde (Electron Microscopy Sciences. Euromedex, Strasbourg, France) in a 0.1 M sodium cacodylate buffer (both Merck, Darmstadt, Germany) (305 mOsm. pH 7.3). After 10 min the mixture ...

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