نتایج جستجو برای: promotion of autophagy
تعداد نتایج: 21177684 فیلتر نتایج به سال:
ATG3 (autophagy-related 3) is an E2-like enzyme essential for autophagy; however, it is unknown whether it has an autophagy-independent function. Here, we report that ATG3 is a relatively stable protein in unstressed cells, but it is degraded in response to DNA-damaging agents such as etoposide or cisplatin. With mass spectrometry and a mutagenesis assay, phosphorylation of tyrosine 203 of ATG3...
Background: FOXO family proteins are important factors in autophagy pathway. Protein kinase-B is an important regulator for this family that can be regulated through exercise training. Therefore, the aim of this study is to investigate the effect of protein kinase-B (PKB) on FOXO autophagy family proteins (FOXO1 and FOXO3a) following high intensity interval training (HIIT) in the left ventricle...
abstract aims: physical inactivity has been identified as the 4th leading risk factor for global mortality causing an estimated of 3.2million deaths per year. this study aimed to assess the physical activity of health volunteers with pender's health promotion model. instrument & methods: this cross-sectional analytical study was performed on 80 health volunteers in torbat-e-jam city, iran,...
Evaluation of ATG7 and LC3 Autophagy Genes Expression in Newly Diagnosed AML patients Background and aim: Autophagy, known as cell death type II, is a housekeeping pathway that currently has been worked on in matters of tumorigenesis and leukemogenesis. Therefore, in this study expression levels of ATG7 and LC3 as two key genes are targeted in AML patients. Material and method: This...
asthma is one of the fastest growing syndromes in many countries and is adding a huge cost to the health care system. increasing reports have linked airway infectious diseases to asthma. influenza is one of the most serious airway infectious diseases and in recent years there have been some serious influenza virus pandemics which caused increased fatality in numerous different populations. dive...
عنوان: بررسی اوضاع فرهنگی گیلان (از انقلاب مشروطیت تا به قدرت رسیدن رضا شاه ) نویسنده: افضل افشاری سال :90-1389 استاد راهنما: دکتر ابوطالب سلطانیان استاد راهنما: دکتر حسن کهنسال واجارگاه چکیده: این پژوهش می کوشد اوضاع فرهنگی گیلان را از دور? مشروطیت تا ظهور رضا خان بررسی نماید و کم و کیف آن را آشکار سازد. انقلاب مشروطیت دو دستاورد مهم فرهنگی را در پی داشت؛ یکی انتشار گسترد? مطبوعات د...
BACKGROUND. Morphological patterns of Paneth cells are a prognostic biomarker in Western Crohn's disease (CD) patients, and are associated with autophagy-associated ATG16L1 and NOD2 variants. We hypothesized that genetic determinants of Paneth cell phenotype in other ethnic CD cohorts are distinct but also involved in autophagy. METHODS. We performed a hypothesis-driven analysis of 56 single nu...
context alpha-1-antitrypsin (a1at) is the most abundant liver-derived, highly polymorphic, glycoprotein in plasma. hereditary deficiency of alpha-1-antitrypsin in plasma (a1atd) is a consequence of accumulation of polymers of a1at mutants in endoplasmic reticulum of hepatocytes and other a1at-producing cells. one of the clinical manifestations of a1atd is liver disease in childhood and cirrhosi...
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