Autophagy, a eukaryotic cellular activity leading to the degradation of cellular components, serves as a defense mechanism against facultative intracellular bacteria as well as a growth niche for the obligate intracellular bacterium Coxiella burnetii. We here demonstrate that the obligate intracellular bacterial pathogen Chlamydia trachomatis lymphogranuloma venereum strongly induced autophagy ...

Introduction The Productive Diversity policy was launched by Paul Keating in 1992 with the objective of increasing Australian business access to, and success in trading with increasingly diverse domestic and export markets. The policy was argued as a ‘win-win’ strategy that could support the needs of Australian businesses in a global trading environment while at the same time, take advantage of...

Contrary to the fairly established notion in the learning sciences that un-scaffolded processes rarely lead to meaningful learning, this study reports a hidden efficacy of such processes and a method for extracting it. Compared to scaffolded, well-structured problem-solving groups, un-scaffolded, ill-structured problem-solving groups struggled with defining and solving the problems. Their discu...

Invention and Productive Failure activities ask students to generate methods that capture the important properties of some given data (e.g., uncertainty) before being taught the expert solution. Invention and Productive Failure activities are a class of scientific inquiry activities in that students create, implement, and evaluate mathematical models based on data. Yet, lacking sufficient inqui...

Introduction: Heart disease or cardiovascular disease (CVD) is a kind of illness that involve heart and/or blood vessels of people throughout the world. The major aim of current study was to show the trend of global scientific activities in the field of CVD during a period of 10 years through 2001-2010. Methods: A scientometrics analysis was carried out to show the world wide activities towards...

The objective of the research is to identify the locational factors that influenced the decision to expand winemaking activity into other regions of Brazil. In recent years, winemaking has expanded into new regions in the state of Rio Grande do Sul (Serra do Sudeste and Campanha) and into the São Francisco River Valley (states of Bahia and Pernambuco) regions where this activity had not previou...

Background: Responsible, productive and competent health workforce is an essential pre-requisite for effective health outcomes and favourable health indicators. Existing on geographical and organizational periphery of the formal health care delivery system, Auxiliary Nurse Midwives (ANMs) operate from subcentres, catering 5000 population in plains and 3000 in hills. Darjeeling district has wide...

Does variety increase happiness? Eight studies examine how the variety among the activities that fill people’s day-to-day lives affects subsequent happiness. The studies demonstrate that whether variety increases or decreases happiness depends on the perceived duration of the time within which the activities occur. For longer time periods (like a day), variety does increase happiness. However, ...

Differences in firm-level productivity explain international activities of non-financial firms quite well. We test whether differences in bank productivity determine international activities of banks. Based on a dataset that allows tracking banks across countries and across different modes of foreign entry, we model the ordered probability of maintaining a commercial presence abroad and the vol...

Much attention has been focused on control of fire in human evolution and the impact of cooking on anatomy, social, and residential arrangements. However, little is known about what transpired when firelight extended the day, creating effective time for social activities that did not conflict with productive time for subsistence activities. Comparison of 174 day and nighttime conversations amon...