Exploring the Immunogenicity and Therapeutic Applications of Boranophosphatemodified RNA: siRNA and RNA Aptamers by Mariam Lucila Sharaf Department of Chemistry Duke University Date:_______________________ Approved: ___________________________ Barbara Ramsay Shaw, Supervisor ___________________________ Katherine J. Franz ___________________________ Thom LaBean ___________________________ Bruce ...

W Paul Bissett', Oscar Schofield\ Curtis D Mobley\ Michael F Crowleyl and Mark A Moline" 'Florida Environmental Research Institute, Tampa, Florida, USA; l(ooslol Ocean ObservQtion Laboratory, Institute of Marine and Coastal Sciences. Rutgers University, New Brunswick, New Jersey, USA; ISequoia Scientific, Inc.. Redmond,Washington, USA; 'Biological Sciences Department, California Polytechnic Sla...

In this paper the design and formal veri cation of the Reliable Computing Platform (RCP), a fault-tolerant computing system for digital ight control applications, are presented. The RCP utilizes NMR-style redundancy to mask faults and internal majority voting to ush the e ects of transient faults. The system is formally speci ed and veri ed using the Ehdm veri cation system. A major goal of thi...

In this paper, an equivariant version of the classical Dold-Thom theorem is proved. Let G be a finite group, X a G-space, and k a covariant coefficient system on G. Then a topological abelian group GX ⊗GF k is constructed by the coend construction. For a G-CW complex X, it is proved that there is a natural isomorphism πi(GX ⊗GF k) ∼= H G i (X; k), where the right hand side is the Bredon equivar...

Two new compounds: 3-β,15-α,23,28-tetrahydroxyolean-12-en-3-O-arabinopyaranoside and 3-β,23,28-trihydroxy-olean-12-en-3-O-β-D-glucopyranoside were isolated from the aerial parts of Ammania auriculata along with the known compounds kaempferol, β-sitosterol-3-O-β- D-glucoside, 2-α,3-β,23-trihydroxyolean-12-en-28-oic acid-28-O-β-D-glucopyranoside, quercetin, kaempferol-3-O-α-L-arabinofuranoside, k...

Infernão Lake, located within the Jataí Ecological Station in Luiz Ant nio Municipal district (São Paulo State, Brazil), is one of the most typical ox-bow lake of the Mogi-Guaçu River, and it presents, as the main feature, its great quantity of aquatic macrophytes, whose intensive development, in the last years practically covered the whole mirror of water. With the purpose to point out the com...

Essential oils extracted from flower petals of palmarosa (Cymbopogon martini), evening primrose (Primula rosea), lavender (Lavandula angustifolia) and tuberose (Polianthus tuberosa) were tested for their antibacterial activities against gram-positive and gram-negative bacteria. Different concentrations of each essential oil ranging from 10-100% were tested. Both gram-positive and gram-negative ...

Sir,?I noticed in the " British Medical Journal" of the 28th September last, page 719, a communication from Mr. Oldacres, M.B.C.S., that by handling the plant named Primula obconica an obstinate rash is produced, attended with dyspeptic symptoms. 1 beg to bring to your notice that there are two plants in this part of the country, very common in shady places, known as the Tragia eannaMna and Tra...