Primary hepatocytes display functional and structural instability in standard monoculture systems. We have previously developed a model in which primary hepatocytes are organized in domains of empirically optimized dimensions and surrounded by murine embryonic fibroblasts (HepatoPac™). Here, we assess the long-term phenotype of freshly isolated and cryopreserved rat hepatocytes in a 96-well Hep...

Primary stability is absence of mobility in the bone bed after mini-implant placement and depends on bone quality among other factors. Bone quality is a subjective term frequently considered as bone density. The aim of this preliminary study was to evaluate bone density in two bovine pelvic regions and verify the primary stability of miniscrews inserted into them. Forty bone blocks were extract...

in this paper we investigate decompositions of submodules in modules over a proufer domain into intersections of quasi-primary and classical quasi-primary submodules. in particular, existence and uniqueness of quasi-primary decompositions in modules over a proufer domain of finite character are proved. proufer domain; primary submodule; quasi-primary submodule; classical quasi-primary; decomposi...

Metabolic networks are characterized by complex interactions and regulatory mechanisms between many individual components. These interactions determine whether a steady state is stable to perturbations. Structural kinetic modeling (SKM) is a framework to analyze the stability of metabolic steady states that allows the study of the system Jacobian without requiring detailed knowledge about indiv...

AIMS This study aims to relate bone density in Hounsfield units (Hu) with the primary implant stability measured by insertion torque (Ncm) and resonance frequency analysis (ISQ). MATERIALS AND METHODS Ten patients were included in this study. A total of 54 implant sites were provided from 10 computerized tomography scans. The computerized tomography scan was used for the preoperative evaluati...

The positive stability and D-stability of singular M-matrices, perturbed by (non-trivial) nonnegative rank one perturbations, is investigated. In special cases positive stability or D-stability can be established. In full generality this is not the case, as illustrated by a counterexample. However, matrices of the mentioned form are shown to be P-matrices. AMS 2010 Subject classifications. Prim...

4.1 Methods of fracture stabilization 17 4.2 Nonoperative fracture management 17 4.2.1 Fracture healing without treatment 4.2.2 Conservative treatment of fractures 4.3 Surgical fixation with relative stability 19 4.3.1 Mechanics of techniques of relative stability 4.3.2 Implants 4.3.3 Mechanobiology of indirect or secondary fracture healing 4.4 Surgical fixation with absolute stability 22 4.4.1...

The primary stability of cementless total hip endoprosthesis is of vital importance for proximate, long-term osteointegration. The extent of micromotions between implant and acetabulum is an indicator of primary stability. Based on this hypothesis, different cementless hip joint endoprosthesis were studied with regard to their micromotions. The primary stability of nine different cementless thr...

We study hedonic coalition formation games in which cooperation among the players is restricted by a graph structure: a subset of players can form a coalition if and only if they are connected in the given graph. We investigate the complexity of finding stable outcomes in such games, for several notions of stability. In particular, we provide an efficient algorithm that finds an individually st...