In 1960 pathologist Robert Gorlin and dermatologist W Goltz from the University of Minnesota, United States; provided basis for diagnosing syndrome, establishing basal cells carcinomas, keratocysts, skeletal malformations as primary criteria syndrome

the primary carcinoma may secondarily invade bone tissue through direct extensions, blood circulation or lymphatic transportation particulary when it is arising from breast, prostate, kidney, thyroid and lung. metastatics tumors of bone are more common than primary tumor of bone. the most common tumor, which metastasizes into bone, is the breast adenocarcinoma. some metastatic tumors of bone in...

background: the nutcracker syndrome represents a clinical condition caused by compression of the left renal vein (lrv) between the superior mesenteric artery (sma) and the aorta. one of its manifestations is left-sided varicocele. the aim of this study is to determine the prevalence of nutcracker syndrome in patients with primary and recurrent high grade left-sided varicocele.   methods: fifty ...