Primary immunodeficiency diseases are rare hereditary conditions that usually occur at a young age; however, secondary immunodeficiency is acquired due to disease, drug treatment and is increasing in frequency among the population. Although periodontal diseases related to these conditions are secondary to other life threatening manifestations, they are very common and easily detectable by the p...

the (bacille calmette-gue´rin) bcg is widely practiced in many countries in pediatric group and is a part of routine vaccination program at birth in ir. iran for prophylaxis against tuberculosis, but its efficacy is a matter of debate in different geographic and ethnic regions. adverse reactions induced by bcg vaccination ranges from bcg adenitis, osteitis, and cold abscess at vaccination site ...

The bacilli Calmette-Guérin (BCG) vaccine is administered to all newborns in countries where tuberculosis is endemic. Immunocompromised hosts, namely patients with human immunodeficiency virus infection or primary immunodeficiencies, are especially prone to serious complications from this vaccine. We report three cases of BCG disease in children with primary immunodeficiencies: one with a parti...

Anti-cytokines autoantibodies (ACAA) are types of against soluble immune factors and may be mirrored by autoimmune disease biomarkers. The manifestation secretion these antibodies is associated to primary immunodeficiency (PID), but also directly or indirectly related infectious occurrence, which could assumed as a consequence cytokine deficiency

INTRODUCTION Primary immunodeficiencies comprise diseases that impair the immune system. Clinical manifestations are characterized by recurrent respiratory infections, which may be complicated by bronchiectasis, peribronchial thickening, abscesses, bullae, and pulmonary fibrosis. The aim of this study was to determine pulmonary complications in pediatric primary immunodeficiency by type. RESULT...

We retrospectively analyzed the outcomes of hematopoietic stem cell transplantation in 7 patients with primary immunodeficiency diseases treated at the National University Hospital, Singapore, over the period from December 1996 to January 2010. The primary immunodeficiency diseases managed were X-linked hyperimmunoglobulin M syndrome (n = 3), severe combined immunodeficiency (n = 1), leukocyte ...