نتایج جستجو برای: primary cutaneous b cell lymphoma
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A 20-year-old woman presented with multiple painless nodular swellings on the skin of the extremities and face, without any systemic symptoms. Biopsy with immunohistochemistry revealed a diagnosis of precursor B-cell lymphoblastic lymphoma. There was no extracutaneous site of involvement. The patient denied chemotherapy and was subsequently lost to follow-up. She presented with symptomatic diss...
Primary cutaneous B-cell lymphomas (CBCL) comprise a group of extranodal non-Hodgkin that are primarily confined to the skin. marginal zone lymphoma (MZL) and follicle center (FCL) associated with rather indolent tumor behavior, while diffuse large lymphoma, leg type (DLBCL-LT) shows an aggressive clinical course. Besides distinct immune-histological features, underlying molecular biology is st...
Background: Lymphoma arises in lymph nodes. Infiltration of malignant lymphomatous cells the organs other than node is termed as extranodal lymphoma (ENL). Almost any organ body can get affected. The most frequently involved system gastrointestinal tract, followed by lung, liver, spleen, bone, and skin. Primary central nervous (CNS) also well documented. Origin tumor from non-lymph-nodal tissue...
PURPOSE To evaluate the role of surgery in patients diagnosed with primary cutaneous B-cell lymphoma (PCBCL) - a rare disease entity. The authors offer a rationale for the use of primary surgical excision in the treatment of isolated cutaneous lymphomas. METHODS A literature review examining the use of primary surgical excision in the treatment of PCBCL was conducted. The lymphoma database at...
Primary cutaneous B-cell lymphomas are a heterogeneous group of mature B-cells neoplasms with tropism for the skin, whose biology and clinical course differ significantly from the equivalent nodal lymphomas. The most indolent forms comprise the primary cutaneous marginal zone and follicle center B-cell lymphomas that despite the excellent prognosis have cutaneous recurrences very commonly. The ...
INTRODUCTION Cytotoxic CD8+ T-cell lymphomas are only rarely encountered and thus remain only poorly characterized. Our aim was to collect and correlate clinical and histological data of CD8+ skin lymphoma infiltrates to obtain a proper subtype assignment of CD8+ skin lymphoma infiltrates and to derive putative prognostic markers thereof. METHODS Formalin-fixed and paraffin-embedded (FFPE) ti...
Categorization of primary cutaneous B-cell lymphomas (PCBCL) other than marginal zone (MZL) represents a diagnostic challenge with relevant prognostic implications. The 2008 WHO lymphoma classification recognizes only primary cutaneous follicular center cell lymphoma (PCFCCL) and primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT), whereas the previous 2005 WHO/EORTC classifi...
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