background. the most common species isolated from primary endodontic infections are black-pigmented bacteria. these species are implicated in apical abscess formation due to their proteolytic activity and are fastidious in nature. therefore, the present study was carried out to evaluate the presence and identification of various pigmented porphyromonas and prevotella species in the infected roo...

The worldwide increase in nonalcoholic fatty liver disease (NAFLD) is a major public health problem. Obesity and diabetes are risk factors for NAFLD the development of fibrosis factor cancer. Periodontal bacteria can also exacerbate NAFLD. We previously reported that amazake, traditional Japanese fermented food, improves quality life (QOL) patients with cirrhosis. In this study, we investigated...

Culture of bronchoalveolar lavage fluid (BALF) is the gold standard for detection of pathogens in the lower airways in cystic fibrosis (CF). However, current culture results do not explain all clinical observations in CF, including negative culture results during pulmonary exacerbation and inflammation in the absence of pathogens. We hypothesize that organisms not routinely identified by cultur...

OBJECTIVES The purpose of this study was to compare microbial profiles of saliva, pooled and site-specific subgingival samples in patients with periodontitis. We tested the hypotheses that saliva can be an alternative to pooled subgingival samples, when screening for presence of periopathogens. DESIGN Site specific subgingival plaque samples (n = 54), pooled subgingival plaque samples (n = 18...

PURPOSE The presence of periodontopathic bacteria is a risk factor for peri-implantitis. The present study examined colonization by periodontopathic bacteria and their transmission from periodontal pockets to osseointegrated implant sulcus. MATERIALS AND METHODS Plaque samples were collected from 105 sites in the 15 patients who participated in the study. Colonization by these bacteria was ex...

P eriodontitis is characterized by gingival inflammation, as well as loss of connective tissue and bone from around the roots of the teeth, which leads to eventual tooth exfoliation. Severe periodontitis often coexists with diabetes and is considered to be the sixth complication of the disease, as both type 1 and type 2 diabetic patients show a threeto fourfold increased risk of periodontitis (...

OBJECTIVES Staphylococcus spp. are postulated to play a role in peri-implantitis. This study aimed to develop a "submucosal" in vitro biofilm model, by integrating two staphylococci into its composition. MATERIALS AND METHODS The standard "subgingival" biofilm contained Actinomyces oris, Fusobacterium nucleatum, Streptococcus oralis, Veillonella dispar, Campylobacter rectus, Prevotella interm...

AIM To compare the early bacterial colonization and soft tissue health of mucosa adjacent to zirconia (ZrO(2)) and titanium (Ti) abutment surfaces in vivo. MATERIALS AND METHODS Twenty edentulous subjects received two endosseous mandibular implants. The implants were fitted with either a ZrO(2) or a Ti abutment (non-submerged implant placement, within-subject comparison, left-right randomizat...

BACKGROUND AND OBJECTIVE The cell-surface lipooligosaccharide (LOS) of Treponema denticola possesses several biological properties. The aim of this study was to investigate the binding properties of T. denticola LOS to extracellular matrix (ECM) proteins, mucosal cells, and oral bacteria. DESIGN LOS was isolated from T. denticola and labeled with tritium. Tritium-labeled LOS was placed in ECM...

Viral and bacterial associations appear to be implicated in the development of periodontal infections. Little information is available describing the periodontopathic agents in root canals with necrotic pulp. In this study, the occurrence and the combinations among herpes simplex virus type 1 (HSV-1) and Dialister pneumosintes, Tannerella forsythia, and Treponema denticola in patients with chro...