The dried fruits of the chaste tree Vitex agnus castus (VAC) were traditionally used by monks as a substitute for pepper and was therefore also called Monk’s pepper. For the last 50 years it is commercially provided for the treatment of premenstrual symptoms, particularly to prevent premenstrual mastodynia (mastalgia). Most studies were performed with the preparation containing an aqueous/ethan...

Methods: The design was a double-blind, placebo-controlled, randomized, multicenter study. 120 patients were included and tested as devised by Steiner. Primary variables were Premenstrual Tension Syndrome self-rating (PMTS-S) and Premenstrual Tension Syndrome observer-rating (PMTS-O). Secondary variables were PMS symptoms evaluated on visual analogue (VAS) scales. Femal tablets 160 mg (twice da...

INTRODUCTION Premenstrual syndrome is one of the most common disorders in women, which includes a group of psychological and physical symptoms. The aim of this study was to examine the impact of combined use of calcium and vitamin B6 on premenstrual syndrome symptoms. METHODS This double blind randomized controlled was carried out on 76 students of Hamadan University of Medical Sciences. Stud...

Outcomes assessed in the review The presence or severity of PMS, evaluated through the use of daily prospective self-administered questionnaires (e.g. Moos Menstrual Distress Questionnaire, Calendar of Premenstrual Experiences, and the Premenstrual Assessment Form), daily visual analogue scales, global assignment after each cycle, or one-time assessment. Interventions were recorded as having po...

BACKGROUND Neurosteroids such as allopregnanolone and pregnanolone are suggested to be of importance for the pathophysiology of premenstrual dysphoric disorder. The aim of this study was to investigate whether the luteal-phase serum concentrations of these neurosteroids are associated with improvement of premenstrual symptoms in 12 women with severe premenstrual syndrome after treatment with lo...

PRIMARY OBJECTIVE To evaluate the effectiveness of Neptune Krill Oil (NKO) for the management of premenstrual syndrome and dysmenorrhea. SECONDARY OBJECTIVE To compare the effectiveness of NKO for the management of premenstrual syndrome and dysmenorrhea with that of omega-3 fish oil. METHODS/DESIGN Double-blind, randomized clinical trial. SETTING Outpatient clinic. PARTICIPANTS Seventy ...

Abst rac t Women are at significantly higher risk for developing post-traumatic stress disorder (PTSD) than men, resulting in increased psychosocial burden and healthcare related costs. Recent research has shown complex interactions between the impact of traumatic experiences, and the reproductive lifecycle in women. For example, women suffering from premenstrual dysphoric disorder (PMDD) who a...

Yoga classes designed for women with premenstrual syndrome are available, but their efficacy is unclear. We investigated the effects of 12 weeks' yoga exercise (yoga intervention) on premenstrual symptoms in menstruating females in Taiwan. Sixty-four subjects completed the yoga intervention, and before and after the intervention filled out a structured self-report questionnaire about their demo...

The inclusion of research diagnostic criteria for premenstrual dysphoric disorder (PMDD) in the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, recognizes the fact that some women have extremely distressing emotional and behavioural symptoms premenstrually. PMDD can be differentiated from premenstrual syndrome (PMS), which presents with milder physical symptoms, headache, an...