INTRODUCTION Acute kidney injury (AKI) is common in neonatal intensive care units (NICU). In recent years, every effort is made for early detection of AKI. Our hypothesis was that serum neutrophil gelatinase-associated lipocalin (sNGAL) may be a reliable screening test for early diagnosis of AKI in premature neonates after perinatal asphyxia. Therefore, our aim was to assess the diagnostic accu...

premature or anemic infants who undergoing hernia repair operation had more chance to have postoperative complications such as apnea as compared with full-term infants. the incidence of respiratory complications among noted infants is more than 30% and postoperative apnea was most common complication among them. in one study, investigators found that gestational and postconceptional age, the pr...

a number of innocent rashes occurs in neonates. they are usually transient and self limited and thus require no therapy but early recognition is important to distinguish these lesions from more serious disorders. in this study, our purpose was to determine the frequency of birthmarks in iranian neonates. the presence of various types of birthmarks was determined in 503 iranian neonates under 72...

Background: The sudden exposure of premature newborns to a cold and dry environment can lead to hypothermia. This study aimed at comparing the effectiveness of two polyethylene covers on the body temperature and oxygen saturation of premature neonates. Methods: This experimental study was conducted on 72 premature newborns in the neonatal int...

OBJECTIVE: The present study was aimed at analyzing the value of the early diagnosis of hemodynamic changes in hemorrhages and hypoxic-ischemic events in premature, very-low-birth-weight neonates through the evaluation of images and resistance index measurement by means of transcranial Doppler ultrasonography. MATERIALS AND METHODS: Fifty premature, very-low-birth-weight neonates were submitted...

Introduction: The influence of nitric oxide (NO) on blood platelets in premature newborns remains largely unexplained. Material and methods: The expression of the activated GPIIb-IIIa complex and P-selectin were monitored by flow cytometry in whole blood platelets originating from 21 premature, 19 full-term neonates and 27 adults. Platelets were incubated with either freshly generated NO, L-arg...

INTRODUCTION Oral feeding is a complex physiological process. Several scales have been developed to assess the ability of the neonate to begin suck feedings and assist caregivers in determining feeding advancement. However, feeding premature neonates remains an ongoing challenge and depends above all on caregivers' feeding expertise. We will evaluate the effect of a nurse training programme on ...

OBJECTIVE Premature birth is an important factor for mortality and morbidity of neonates. This study was designed to evaluate the outcome of preterm neonates who needed neonatal intensive care (NICU) hospitalization after 6 yr at their entrance to the school. MATERIALS & METHODS This cross sectional study was conducted on premature neonates consecutively hospitalized in NICU of Valie Asr Hosp...

BACKGROUND AND OBJECTIVE Major changes in cytochrome P450 (CYP) 3A activity may be expected in the first few months of life with, later, relatively limited changes. In this analysis we studied the maturation of in vivo CYP3A-mediated clearance of midazolam, as model drug, from preterm neonates of 26 weeks gestational age (GA) to adults. METHODS Pharmacokinetic data after intravenous administr...